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| Official Gene Symbol | Other Aliases |
|---|---|
| RRM2 | RR2 |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 389 | 44878 |
| Protein Name |
|---|
| Ribonucleoside-diphosphate reductase subunit M2 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MLSLRVPLAP | ITDPQQLQLS | PLKGLSLVDK | ENTPPALSGT | RVLASKTARR |
| 60 | 70 | 80 | 90 | 100 |
| IFQEPTEPKT | KAAAPGVEDE | PLLRENPRRF | VIFPIEYHDI | WQMYKKAEAS |
| 110 | 120 | 130 | 140 | 150 |
| FWTAEEVDLS | KDIQHWESLK | PEERYFISHV | LAFFAASDGI | VNENLVERFS |
| 160 | 170 | 180 | 190 | 200 |
| QEVQITEARC | FYGFQIAMEN | IHSEMYSLLI | DTYIKDPKER | EFLFNAIETM |
| 210 | 220 | 230 | 240 | 250 |
| PCVKKKADWA | LRWIGDKEAT | YGERVVAFAA | VEGIFFSGSF | ASIFWLKKRG |
| 260 | 270 | 280 | 290 | 300 |
| LMPGLTFSNE | LISRDEGLHC | DFACLMFKHL | VHKPSEERVR | EIIINAVRIE |
| 310 | 320 | 330 | 340 | 350 |
| QEFLTEALPV | KLIGMNCTLM | KQYIEFVADR | LMLELGFSKV | FRVENPFDFM |
| 360 | 370 | 380 | 389 | |
| ENISLEGKTN | FFEKRVGEYQ | RMGVMSSPTE | NSFTLDADF |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA. Schoenherr RM, Saul RG, Whiteaker JR, Yan P, Whiteley GR, Paulovich AG. Mol Cell Proteomics. 2015 Feb;14(2):382-98. doi: 10.1074/mcp.O114.043133. Epub 2014 Dec 15. PMID: 25512614
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b11 (2+) | 14 | 4.5 | 8.1 | 10.5 | 5.7 | 9 | 17.5 | 7.3 | 12.1 | 15 | 15 | 15 |
| y9 (2+) | 16.1 | 9 | 9.7 | 17 | 8.9 | 10.7 | 23.4 | 12.7 | 14.4 | 15 | 15 | 15 |
| y11 (2+) | 9.5 | 5.6 | 4.4 | 8.1 | 8 | 5.9 | 12.5 | 9.8 | 7.4 | 15 | 15 | 15 |
| y2 (1+) | 15 | 7.6 | 5.5 | 14.4 | 7.8 | 7.9 | 20.8 | 10.9 | 9.6 | 15 | 15 | 15 |
| sum | 5.7 | 3.7 | 3.3 | 8.1 | 4.7 | 5.1 | 9.9 | 6 | 6.1 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage. Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG. Radiat Res. 2018 Feb 23. doi: 10.1667/RR14963.1. [Epub ahead of print]
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y10 (1+) | 14.6 | 9.9 | 10.1 | 20.2 | 10.8 | 18.4 | 24.9 | 14.7 | 21 | 15 | 15 | 15 |
| y9 (1+) | 11.2 | 11.3 | 13.6 | 15 | 13.2 | 11.8 | 18.7 | 17.4 | 18 | 15 | 15 | 15 |
| y4 (1+) | 12.5 | 10.3 | 10.4 | 13 | 10.7 | 12.2 | 18 | 14.9 | 16 | 15 | 15 | 15 |
| b3 (1+) | 20.2 | 9 | 12.7 | 19.6 | 8.7 | 16.1 | 28.1 | 12.5 | 20.5 | 15 | 15 | 15 |
| sum | 7.7 | 7.3 | 7.5 | 8.1 | 7.1 | 10.2 | 11.2 | 10.2 | 12.7 | 15 | 15 | 15 |
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