| Official Gene Symbol | Other Aliases |
|---|---|
| EIF4E | EIF4EL1, EIF4F |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 217 | 25097 |
| Protein Name |
|---|
| Eukaryotic translation initiation factor 4E |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MATVEPETTP | TPNPPTTEEE | KTESNQEVAN | PEHYIKHPLQ | NRWALWFFKN |
| 60 | 70 | 80 | 90 | 100 |
| DKSKTWQANL | RLISKFDTVE | DFWALYNHIQ | LSSNLMPGCD | YSLFKDGIEP |
| 110 | 120 | 130 | 140 | 150 |
| MWEDEKNKRG | GRWLITLNKQ | QRRSDLDRFW | LETLLCLIGE | SFDDYSDDVC |
| 160 | 170 | 180 | 190 | 200 |
| GAVVNVRAKG | DKIAIWTTEC | ENREAVTHIG | RVYKERLGLP | PKIVIGYQSH |
| 210 | 217 | |||
| ADTATKSGST | TKNRFVV |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b2 (1+) | 7.8 | 3 | 4 | 6.4 | 4.3 | 3.1 | 10.1 | 5.2 | 5.1 | 16 | 16 | 17 |
| y10 (2+) | 9.3 | 6.8 | 6.1 | 10.8 | 5.9 | 6.8 | 14.3 | 9 | 9.1 | 16 | 16 | 17 |
| y11 (2+) | 8.5 | 5.3 | 5.9 | 8.3 | 5.6 | 6.8 | 11.9 | 7.7 | 9 | 16 | 16 | 17 |
| y12 (2+) | 7.6 | 5.2 | 2.7 | 8 | 5.4 | 3.9 | 11 | 7.5 | 4.7 | 16 | 16 | 17 |
| y13 (2+) | 10.8 | 6.1 | 4.6 | 10.4 | 6.1 | 4.3 | 15 | 8.6 | 6.3 | 16 | 16 | 17 |
| sum | 5.8 | 3.6 | 2.1 | 5 | 3.4 | 2.3 | 7.7 | 5 | 3.1 | 16 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b2 (1+) | 3.1 | 2.5 | 7.3 | 7 | 5.9 |
| y10 (2+) | 4.9 | 5.9 | 13.8 | 6.5 | 17.9 |
| y11 (2+) | 3.3 | 7.6 | 7.2 | 6.9 | 2.8 |
| y12 (2+) | 5.4 | 6.2 | 4.9 | 7.5 | 4 |
| y13 (2+) | 4.5 | 7.9 | 2.2 | 4.7 | 2.1 |
| sum | 3.5 | 4.4 | 2.7 | 5.1 | 3.2 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b2 (1+) | 4.7 | 5.2 |
| y10 (2+) | 9.1 | 8.2 |
| y11 (2+) | 5.9 | 4 |
| y12 (2+) | 5.7 | 3.8 |
| y13 (2+) | 4.9 | 4.8 |
| sum | 3.9 | 2.3 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b2 (1+) | 9.4 | 30 | 31.4 |
| y10 (2+) | 1.1 | 20.4 | 20.4 |
| y11 (2+) | 19.9 | 34.7 | 40 |
| y12 (2+) | 17.7 | 32.9 | 37.4 |
| y13 (2+) | 9.7 | 25.6 | 27.4 |
| sum | 14.1 | 28.7 | 32 |
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