| Official Gene Symbol | Other Aliases |
|---|---|
| EIF6 | EIF3A, ITGB4BP |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 245 | 26599 |
| Protein Name |
|---|
| Eukaryotic translation initiation factor 6 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MAVRASFENN | CEIGCFAKLT | NTYCLVAIGG | SENFYSVFEG | ELSDTIPVVH |
| 60 | 70 | 80 | 90 | 100 |
| ASIAGCRIIG | RMCVGNRHGL | LVPNNTTDQE | LQHIRNSLPD | TVQIRRVEER |
| 110 | 120 | 130 | 140 | 150 |
| LSALGNVTTC | NDYVALVHPD | LDRETEEILA | DVLKVEVFRQ | TVADQVLVGS |
| 160 | 170 | 180 | 190 | 200 |
| YCVFSNQGGL | VHPKTSIEDQ | DELSSLLQVP | LVAGTVNRGS | EVIAAGMVVN |
| 210 | 220 | 230 | 240 | 245 |
| DWCAFCGLDT | TSTELSVVES | VFKLNEAQPS | TIATSMRDSL | IDSLT |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b4 (1+) | 16.3 | 6.1 | 6.9 | 22.6 | 6.4 | 6.6 | 27.9 | 8.8 | 9.5 | 15 | 16 | 17 |
| b5 (1+) | 19.4 | 5.7 | 3.8 | 24.3 | 5.8 | 6.2 | 31.1 | 8.1 | 7.3 | 15 | 16 | 17 |
| y10 (2+) | 17.5 | 6.7 | 8.2 | 23.4 | 7.2 | 5.8 | 29.2 | 9.8 | 10 | 15 | 16 | 17 |
| y11 (2+) | 18.5 | 5.2 | 8 | 23.2 | 5.4 | 7.6 | 29.7 | 7.5 | 11 | 15 | 16 | 17 |
| y9 (2+) | 17.9 | 6.4 | 5.9 | 23.8 | 5.8 | 5.7 | 29.8 | 8.6 | 8.2 | 15 | 16 | 17 |
| sum | 16.9 | 3.1 | 2 | 21.6 | 3.4 | 3.4 | 27.4 | 4.6 | 3.9 | 15 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b4 (1+) | 7.1 | 6.9 | 70.4 | 2.8 | 9.9 |
| b5 (1+) | 1.8 | 7 | 235.2 | 6.4 | 1.8 |
| y10 (2+) | 6.2 | 5.6 | 216.6 | 6.4 | 4 |
| y11 (2+) | 9.3 | 5 | 125.3 | 8.6 | 0.7 |
| y9 (2+) | 2 | 12.1 | 150.7 | 8.3 | 2.1 |
| sum | 1.7 | 3.5 | 43.1 | 3.5 | 0.9 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b4 (1+) | 17.3 | 38.4 |
| b5 (1+) | 43.2 | 84.3 |
| y10 (2+) | 40.7 | 81 |
| y11 (2+) | 25.7 | 71 |
| y9 (2+) | 31.2 | 45.9 |
| sum | 9.4 | 22.4 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b4 (1+) | 30.9 | 48.7 | 57.7 |
| b5 (1+) | 5 | 36 | 36.3 |
| y10 (2+) | 29.8 | 33.3 | 44.7 |
| y11 (2+) | 62.4 | 46.6 | 77.9 |
| y9 (2+) | 12.3 | 35.8 | 37.9 |
| sum | 6.9 | 36.6 | 37.2 |
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