| Official Gene Symbol | Other Aliases |
|---|---|
| PHB1 | PHB |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 272 | 29804 |
| Protein Name |
|---|
| Prohibitin 1 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MAAKVFESIG | KFGLALAVAG | GVVNSALYNV | DAGHRAVIFD | RFRGVQDIVV |
| 60 | 70 | 80 | 90 | 100 |
| GEGTHFLIPW | VQKPIIFDCR | SRPRNVPVIT | GSKDLQNVNI | TLRILFRPVA |
| 110 | 120 | 130 | 140 | 150 |
| SQLPRIFTSI | GEDYDERVLP | SITTEILKSV | VARFDAGELI | TQRELVSRQV |
| 160 | 170 | 180 | 190 | 200 |
| SDDLTERAAT | FGLILDDVSL | THLTFGKEFT | EAVEAKQVAQ | QEAERARFVV |
| 210 | 220 | 230 | 240 | 250 |
| EKAEQQKKAA | IISAEGDSKA | AELIANSLAT | AGDGLIELRK | LEAAEDIAYQ |
| 260 | 270 | 272 | ||
| LSRSRNITYL | PAGQSVLLQL | PQ |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b2 (1+) | 10.2 | 6 | 3.9 | 9.1 | 5.8 | 6.4 | 13.7 | 8.3 | 7.5 | 16 | 16 | 17 |
| y3 (1+) | 11.9 | 4.6 | 3 | 11.2 | 6.6 | 5.5 | 16.3 | 8 | 6.3 | 16 | 16 | 17 |
| y4 (1+) | 7 | 6.4 | 6.1 | 6.9 | 7.4 | 6.4 | 9.8 | 9.8 | 8.8 | 16 | 16 | 17 |
| y5 (1+) | 8.6 | 5.3 | 4.5 | 8.3 | 6.6 | 4.4 | 12 | 8.5 | 6.3 | 16 | 16 | 17 |
| y8 (1+) | 9.1 | 3.8 | 4.4 | 9.6 | 4.3 | 5.6 | 13.2 | 5.7 | 7.1 | 16 | 16 | 17 |
| sum | 5.2 | 2.8 | 1.9 | 4.9 | 2.8 | 2.1 | 7.1 | 4 | 2.8 | 16 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b2 (1+) | 8.7 | 9.6 | 3.6 | 3.2 | 11.2 |
| y3 (1+) | 4.6 | 2.8 | 4.5 | 9.5 | 8.8 |
| y4 (1+) | 6.8 | 6.8 | 4.1 | 6.8 | 5.5 |
| y5 (1+) | 6.9 | 4.5 | 6.1 | 5.6 | 7.9 |
| y8 (1+) | 3.2 | 6.3 | 5.8 | 13.5 | 5 |
| sum | 2.6 | 2.5 | 1.7 | 1.8 | 1.8 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b2 (1+) | 7.7 | 6.1 |
| y3 (1+) | 5.5 | 5.6 |
| y4 (1+) | 6.1 | 5.3 |
| y5 (1+) | 5.9 | 6.4 |
| y8 (1+) | 6.7 | 5.8 |
| sum | 2.1 | 2.1 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b2 (1+) | 15.1 | 25.9 | 30 |
| y3 (1+) | 0.9 | 24.6 | 24.6 |
| y4 (1+) | 3.7 | 21.2 | 21.5 |
| y5 (1+) | 10.9 | 28.5 | 30.5 |
| y8 (1+) | 15.9 | 26 | 30.5 |
| sum | 0.4 | 25.2 | 25.2 |
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