Official Gene Symbol | Other Aliases |
---|---|
NBN | NBS, NBS1, P95 |
Sequence Length (AA) | Molecular Weight (Da) |
---|---|
754 | 84959 |
Protein Name |
---|
Nibrin |
Sources | |
---|---|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
10 | 20 | 30 | 40 | 50 |
MWKLLPAAGP | AGGEPYRLLT | GVEYVVGRKN | CAILIENDQS | ISRNHAVLTA |
60 | 70 | 80 | 90 | 100 |
NFSVTNLSQT | DEIPVLTLKD | NSKYGTFVNE | EKMQNGFSRT | LKSGDGITFG |
110 | 120 | 130 | 140 | 150 |
VFGSKFRIEY | EPLVACSSCL | DVSGKTALNQ | AILQLGGFTV | NNWTEECTHL |
160 | 170 | 180 | 190 | 200 |
VMVSVKVTIK | TICALICGRP | IVKPEYFTEF | LKAVESKKQP | PQIESFYPPL |
210 | 220 | 230 | 240 | 250 |
DEPSIGSKNV | DLSGRQERKQ | IFKGKTFIFL | NAKQHKKLSS | AVVFGGGEAR |
260 | 270 | 280 | 290 | 300 |
LITEENEEEH | NFFLAPGTCV | VDTGITNSQT | LIPDCQKKWI | QSIMDMLQRQ |
310 | 320 | 330 | 340 | 350 |
GLRPIPEAEI | GLAVIFMTTK | NYCDPQGHPS | TGLKTTTPGP | SLSQGVSVDE |
360 | 370 | 380 | 390 | 400 |
KLMPSAPVNT | TTYVADTESE | QADTWDLSER | PKEIKVSKME | QKFRMLSQDA |
410 | 420 | 430 | 440 | 450 |
PTVKESCKTS | SNNNSMVSNT | LAKMRIPNYQ | LSPTKLPSIN | KSKDRASQQQ |
460 | 470 | 480 | 490 | 500 |
QTNSIRNYFQ | PSTKKRERDE | ENQEMSSCKS | ARIETSCSLL | EQTQPATPSL |
510 | 520 | 530 | 540 | 550 |
WKNKEQHLSE | NEPVDTNSDN | NLFTDTDLKS | IVKNSASKSH | AAEKLRSNKK |
560 | 570 | 580 | 590 | 600 |
REMDDVAIED | EVLEQLFKDT | KPELEIDVKV | QKQEEDVNVR | KRPRMDIETN |
610 | 620 | 630 | 640 | 650 |
DTFSDEAVPE | SSKISQENEI | GKKRELKEDS | LWSAKEISNN | DKLQDDSEML |
660 | 670 | 680 | 690 | 700 |
PKKLLLTEFR | SLVIKNSTSR | NPSGINDDYG | QLKNFKKFKK | VTYPGAGKLP |
710 | 720 | 730 | 740 | 750 |
HIIGGSDLIA | HHARKNTELE | EWLRQEMEVQ | NQHAKEESLA | DDLFRYNPYL |
754 | ||||
KRRR |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich U, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG. Immobilized metal affinity chromatography coupled to multiple reaction monitoring enables reproducible quantification of phospho-signaling. Molecular and Cellular Proteomics. mcp.O115.054940
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
b7-98 (1+) | 52.6 | 14.9 | 37.6 | 52.5 | 13.6 | 31.9 | 74.3 | 20.2 | 49.3 | 15 | 24 | 15 |
y8 (2+) | 14.4 | 12 | 16.9 | 38.1 | 11.6 | 21.2 | 40.7 | 16.7 | 27.1 | 15 | 24 | 15 |
y9 (2+) | 22.8 | 7.3 | 7.8 | 29.3 | 11 | 8.9 | 37.1 | 13.2 | 11.8 | 15 | 24 | 15 |
sum | 20 | 7.2 | 8.1 | 27.9 | 10 | 10.4 | 34.3 | 12.3 | 13.2 | 15 | 24 | 15 |
Data source: Panorama
View Details (opens in a new window)
A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage. Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG. Radiat Res. 2018 Feb 23. doi: 10.1667/RR14963.1. [Epub ahead of print]
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
y7 (1+) | 19.9 | 8.5 | 7.4 | 20.3 | 8.3 | 7.6 | 28.4 | 11.9 | 10.6 | 15 | 15 | 15 |
y8 (1+) | 11.9 | 9.6 | 4.7 | 23.3 | 15.8 | 10.7 | 26.2 | 18.5 | 11.7 | 15 | 15 | 15 |
y4 (1+) | 28.5 | 10.5 | 5 | 35.1 | 14.8 | 10.2 | 45.2 | 18.1 | 11.4 | 15 | 15 | 15 |
sum | 13.6 | 7.6 | 4 | 17.8 | 12.1 | 8.8 | 22.4 | 14.3 | 9.7 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage. Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG. Radiat Res. 2018 Feb 23. doi: 10.1667/RR14963.1. [Epub ahead of print]
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
y8 (2+) | 19 | 24.5 | 13 | 38 | 27.3 | 20.9 | 42.5 | 36.7 | 24.6 | 15 | 15 | 15 |
y8 (1+) | 18.2 | 13 | 9.8 | 42.5 | 18 | 12.1 | 46.2 | 22.2 | 15.6 | 15 | 15 | 15 |
y9-98 (2+) | 17.6 | 11.1 | 8.2 | 47.2 | 14.5 | 12.7 | 50.4 | 18.3 | 15.1 | 15 | 15 | 15 |
y8-98 (1+) | 32 | 13.3 | 11.1 | 47.2 | 13.7 | 20 | 57 | 19.1 | 22.9 | 15 | 15 | 15 |
sum | 12.6 | 11.5 | 6.8 | 42.1 | 15.3 | 12.5 | 43.9 | 19.1 | 14.2 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich U, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG. Immobilized metal affinity chromatography coupled to multiple reaction monitoring enables reproducible quantification of phospho-signaling. Molecular and Cellular Proteomics. mcp.O115.054940
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
y13 (2+) | 28.6 | 8 | 10.1 | 23.1 | 11.3 | 14.8 | 36.8 | 13.8 | 17.9 | 15 | 24 | 15 |
y14 (2+) | 33.1 | 8.7 | 9.6 | 24.2 | 10.4 | 12.2 | 41 | 13.6 | 15.5 | 15 | 24 | 15 |
y15 (2+) | 48.5 | 11.4 | 8.5 | 40.3 | 11.6 | 14.1 | 63.1 | 16.3 | 16.5 | 15 | 24 | 15 |
sum | 32.1 | 8.2 | 8.3 | 20.9 | 9.6 | 12.1 | 38.3 | 12.6 | 14.7 | 15 | 24 | 15 |
Data source: Panorama
View Details (opens in a new window)
A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage. Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG. Radiat Res. 2018 Feb 23. doi: 10.1667/RR14963.1. [Epub ahead of print]
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
y9 (1+) | 86.1 | 26.9 | 20.6 | 90.6 | 28.8 | 20 | 125 | 39.4 | 28.7 | 15 | 15 | 15 |
y12 (2+) | 72.5 | 49.6 | 54.3 | 64.7 | 53.6 | 76.5 | 97.2 | 73 | 93.8 | 15 | 15 | 15 |
y14 (2+) | 25.5 | 14.5 | 17.3 | 25.5 | 14.2 | 16.7 | 36.1 | 20.3 | 24 | 15 | 15 | 15 |
sum | 23.1 | 12.1 | 16.7 | 22.9 | 12.9 | 16.3 | 32.5 | 17.7 | 23.3 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage. Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG. Radiat Res. 2018 Feb 23. doi: 10.1667/RR14963.1. [Epub ahead of print]
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
y13 (2+) | 28.1 | 11.5 | 20 | 39.3 | 10.8 | 16.5 | 48.3 | 15.8 | 25.9 | 15 | 15 | 15 |
y14 (2+) | 22 | 8.5 | 7.8 | 27.2 | 10.1 | 7 | 35 | 13.2 | 10.5 | 15 | 15 | 15 |
y15 (2+) | 33.1 | 10.6 | 7.9 | 38.9 | 14.7 | 13.1 | 51.1 | 18.1 | 15.3 | 15 | 15 | 15 |
y5 (1+) | 44.8 | 8.8 | 13.9 | 47 | 8.6 | 13.5 | 64.9 | 12.3 | 19.4 | 15 | 15 | 15 |
sum | 12.5 | 6.6 | 7.1 | 24.3 | 8.3 | 5.9 | 27.3 | 10.6 | 9.2 | 15 | 15 | 15 |
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