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Overview Data source: UniProt

Official Gene Symbol Other Aliases
BIRC2 API1,IAP2,MIHB,RNF48
Sequence Length (AA) Molecular Weight (Da)
618 69900
Protein Name
Baculoviral IAP repeat-containing protein 2
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM
60 70 80 90 100
STYSTFPAGV PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKLGDSPI
110 120 130 140 150
QKHKQLYPSC SFIQNLVSAS LGSTSKNTSP MRNSFAHSLS PTLEHSSLFS
160 170 180 190 200
GSYSSLSPNP LNSRAVEDIS SSRTNPYSYA MSTEEARFLT YHMWPLTFLS
210 220 230 240 250
PSELARAGFY YIGPGDRVAC FACGGKLSNW EPKDDAMSEH RRHFPNCPFL
260 270 280 290 300
ENSLETLRFS ISNLSMQTHA ARMRTFMYWP SSVPVQPEQL ASAGFYYVGR
310 320 330 340 350
NDDVKCFCCD GGLRCWESGD DPWVEHAKWF PRCEFLIRMK GQEFVDEIQG
360 370 380 390 400
RYPHLLEQLL STSDTTGEEN ADPPIIHFGP GESSSEDAVM MNTPVVKSAL
410 420 430 440 450
EMGFNRDLVK QTVQSKILTT GENYKTVNDI VSALLNAEDE KREEEKEKQA
460 470 480 490 500
EEMASDDLSL IRKNRMALFQ QLTCVLPILD NLLKANVINK QEHDIIKQKT
510 520 530 540 550
QIPLQARELI DTILVKGNAA ANIFKNCLKE IDSTLYKNLF VDKNMKYIPT
560 570 580 590 600
EDVSGLSLEE QLRRLQEERT CKVCMDKEVS VVFIPCGHLV VCQECAPSLR
610 618
KCPICRGIIK GTVRTFLS

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-790 Collapse assay details

Data source: Panorama

Official Gene Symbol
BIRC2
Peptide Sequence
AVEDISSSR
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
165
Peptide End
173
CPTAC ID
CPTAC-790
Peptide Molecular Mass
962.4669
Species
Homo sapiens (Human)
Assay Type
Direct PRM
Matrix
Pooled patient derived xenograft breast tumor digest
Submitting Laboratory
Washington University in St. Louis
Submitting Lab PI
Reid Townsend

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TripleTOF 5600+ (SCIEX)
Internal Standard
Peptide
Peptide Standard Purity
Crude
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
2DPlus nano-LC (Eksigent)
Column Packing
ChromXP C18-CL, 3 µm, 120 Å
Column Dimensions
200 µm x 15 cm
Flow Rate
800 nL/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y4 (1+) 11.4 6.1 5 11.2 3.9 5 16 7.2 7.1 15 15 15
y5 (1+) 8 6.5 3.7 9.7 6.4 4 12.6 9.1 5.4 15 15 15
y6 (1+) 7.6 8.9 3.2 7.2 8.8 3.6 10.5 12.5 4.8 15 15 15
y7 (1+) 6.2 5 5.2 7.1 4.5 7 9.4 6.7 8.7 15 15 15
sum 4.2 4.1 2.5 3.3 4 3.1 5.3 5.7 4 15 15 15

Additional Resources and Comments


Assay Details for CPTAC-791 Collapse assay details

Data source: Panorama

Official Gene Symbol
BIRC2
Peptide Sequence
LGDSPIQK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
95
Peptide End
102
CPTAC ID
CPTAC-791
Peptide Molecular Mass
856.4654
Species
Homo sapiens (Human)
Assay Type
Direct PRM
Matrix
Pooled patient derived xenograft breast tumor digest
Submitting Laboratory
Washington University in St. Louis
Submitting Lab PI
Reid Townsend

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TripleTOF 5600+ (SCIEX)
Internal Standard
Peptide
Peptide Standard Purity
Crude
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
2DPlus nano-LC (Eksigent)
Column Packing
ChromXP C18-CL, 3 µm, 120 Å
Column Dimensions
200 µm x 15 cm
Flow Rate
800 nL/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

Loader

Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y3 (1+) 27.1 16.2 12.4 28.1 17.7 15.5 39 24 19.8 15 15 15
y4 (1+) 8.4 7.4 5.6 8.1 7.3 4.7 11.7 10.4 7.3 15 15 15
y5 (1+) 7.4 4.2 4.9 10 4.4 4 12.4 6.1 6.3 15 15 15
y6 (1+) 10.4 7.4 6.4 9.7 8 8.5 14.2 10.9 10.6 15 15 15
y7 (1+) 6.4 5.9 4.2 7.1 4.6 5.4 9.6 7.5 6.8 15 15 15
b5 (1+) 18.7 11.4 11.3 21.1 13.4 11.3 28.2 17.6 16 15 15 15
b3 (1+) 27.2 17.8 14 27.5 16.9 14.5 38.7 24.5 20.2 15 15 15
sum 2.1 4 2.4 2.7 3.1 3.1 3.4 5.1 3.9 15 15 15

Additional Resources and Comments