| Official Gene Symbol | Other Aliases |
|---|---|
| MAP3K11 | MLK3, PTK1, SPRK |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 847 | 92688 |
| Protein Name |
|---|
| Mitogen-activated protein kinase kinase kinase 11 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MEPLKSLFLK | SPLGSWNGSG | SGGGGGGGGG | RPEGSPKAAG | YANPVWTALF |
| 60 | 70 | 80 | 90 | 100 |
| DYEPSGQDEL | ALRKGDRVEV | LSRDAAISGD | EGWWAGQVGG | QVGIFPSNYV |
| 110 | 120 | 130 | 140 | 150 |
| SRGGGPPPCE | VASFQELRLE | EVIGIGGFGK | VYRGSWRGEL | VAVKAARQDP |
| 160 | 170 | 180 | 190 | 200 |
| DEDISVTAES | VRQEARLFAM | LAHPNIIALK | AVCLEEPNLC | LVMEYAAGGP |
| 210 | 220 | 230 | 240 | 250 |
| LSRALAGRRV | PPHVLVNWAV | QIARGMHYLH | CEALVPVIHR | DLKSNNILLL |
| 260 | 270 | 280 | 290 | 300 |
| QPIESDDMEH | KTLKITDFGL | AREWHKTTQM | SAAGTYAWMA | PEVIKASTFS |
| 310 | 320 | 330 | 340 | 350 |
| KGSDVWSFGV | LLWELLTGEV | PYRGIDCLAV | AYGVAVNKLT | LPIPSTCPEP |
| 360 | 370 | 380 | 390 | 400 |
| FAQLMADCWA | QDPHRRPDFA | SILQQLEALE | AQVLREMPRD | SFHSMQEGWK |
| 410 | 420 | 430 | 440 | 450 |
| REIQGLFDEL | RAKEKELLSR | EEELTRAARE | QRSQAEQLRR | REHLLAQWEL |
| 460 | 470 | 480 | 490 | 500 |
| EVFERELTLL | LQQVDRERPH | VRRRRGTFKR | SKLRARDGGE | RISMPLDFKH |
| 510 | 520 | 530 | 540 | 550 |
| RITVQASPGL | DRRRNVFEVG | PGDSPTFPRF | RAIQLEPAEP | GQAWGRQSPR |
| 560 | 570 | 580 | 590 | 600 |
| RLEDSSNGER | RACWAWGPSS | PKPGEAQNGR | RRSRMDEATW | YLDSDDSSPL |
| 610 | 620 | 630 | 640 | 650 |
| GSPSTPPALN | GNPPRPSLEP | EEPKRPVPAE | RGSSSGTPKL | IQRALLRGTA |
| 660 | 670 | 680 | 690 | 700 |
| LLASLGLGRD | LQPPGGPGRE | RGESPTTPPT | PTPAPCPTEP | PPSPLICFSL |
| 710 | 720 | 730 | 740 | 750 |
| KTPDSPPTPA | PLLLDLGIPV | GQRSAKSPRR | EEEPRGGTVS | PPPGTSRSAP |
| 760 | 770 | 780 | 790 | 800 |
| GTPGTPRSPP | LGLISRPRPS | PLRSRIDPWS | FVSAGPRPSP | LPSPQPAPRR |
| 810 | 820 | 830 | 840 | 847 |
| APWTLFPDSD | PFWDSPPANP | FQGGPQDCRA | QTKDMGAQAP | WVPEAGP |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
loading
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 7 | 4.2 | 6.5 | 7 | 6.6 | 5.5 | 9.9 | 7.8 | 8.5 | 15 | 15 | 15 |
| y10 (1+) | 5 | 3.4 | 3.9 | 8.7 | 4.2 | 3.8 | 10 | 5.4 | 5.4 | 15 | 15 | 15 |
| y11 (1+) | 14.5 | 6.4 | 6.4 | 17.5 | 14 | 6.6 | 22.7 | 15.4 | 9.2 | 15 | 15 | 15 |
| y12 (1+) | 13.8 | 13.4 | 9 | 9.2 | 14.8 | 9.1 | 16.6 | 20 | 12.8 | 15 | 15 | 15 |
| b3 (1+) | 10.4 | 6.8 | 8.8 | 10.7 | 7.1 | 9.5 | 14.9 | 9.8 | 12.9 | 15 | 15 | 15 |
| sum | 4.7 | 3.5 | 2.9 | 5.6 | 4.6 | 2.9 | 7.3 | 5.8 | 4.1 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y5 (1+) | 6 | 3.6 | 5.9 | 10.4 | 3.7 | 5.9 | 12 | 5.2 | 8.3 | 15 | 15 | 15 |
| y6 (1+) | 4.6 | 2.6 | 4.6 | 9.4 | 5.5 | 5.3 | 10.5 | 6.1 | 7 | 15 | 15 | 15 |
| y7 (1+) | 8.6 | 3.3 | 3.9 | 8.4 | 4.9 | 4.8 | 12 | 5.9 | 6.2 | 15 | 15 | 15 |
| y8 (1+) | 6.1 | 2.5 | 3.4 | 8.7 | 4.1 | 3.7 | 10.6 | 4.8 | 5 | 15 | 15 | 15 |
| b3 (1+) | 14.5 | 8.8 | 9.4 | 19.4 | 7.8 | 11.7 | 24.2 | 11.8 | 15 | 15 | 15 | 15 |
| sum | 4.7 | 1.8 | 3.2 | 6.8 | 3.8 | 3.9 | 8.3 | 4.2 | 5 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b3 (1+) | 34.2 | 43.6 | 28.3 | 32.8 | 48.9 | 31.7 | 47.4 | 65.5 | 42.5 | 15 | 15 | 15 |
| y7 (1+) | 15.4 | 12.3 | 11.7 | 15.1 | 12.5 | 11 | 21.6 | 17.5 | 16.1 | 15 | 15 | 15 |
| y6 (1+) | 21.7 | 9.2 | 13.9 | 23.5 | 8.5 | 12.4 | 32 | 12.5 | 18.6 | 15 | 15 | 15 |
| sum | 12.7 | 6.6 | 8.8 | 13.8 | 6.2 | 8.2 | 18.8 | 9.1 | 12 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y4 (1+) | 14.1 | 10.7 | 6.6 | 13.9 | 9.4 | 7.5 | 19.8 | 14.2 | 10 | 15 | 15 | 15 |
| y5 (1+) | 8.5 | 3.5 | 3.5 | 8.7 | 3.8 | 3.8 | 12.2 | 5.2 | 5.2 | 15 | 15 | 15 |
| y6 (1+) | 22.2 | 14.8 | 14.1 | 23.1 | 15.8 | 15.8 | 32 | 21.6 | 21.2 | 15 | 15 | 15 |
| y7 (1+) | 15.7 | 11.7 | 10.9 | 15.5 | 12.9 | 13.2 | 22.1 | 17.4 | 17.1 | 15 | 15 | 15 |
| y9 (1+) | 31 | 11.1 | 16.1 | 30.7 | 12.7 | 17.4 | 43.6 | 16.9 | 23.7 | 15 | 15 | 15 |
| sum | 8.8 | 4.2 | 2.9 | 8.3 | 4.2 | 3 | 12.1 | 5.9 | 4.2 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y4 (1+) | 10.4 | 4.6 | 9.4 | 10.7 | 7.1 | 8 | 14.9 | 8.5 | 12.3 | 15 | 15 | 15 |
| y5 (1+) | 7.8 | 2.7 | 4.4 | 7.2 | 5.6 | 4.6 | 10.6 | 6.2 | 6.4 | 15 | 15 | 15 |
| y6 (1+) | 8.6 | 4.3 | 4.3 | 8.3 | 5 | 5.8 | 12 | 6.6 | 7.2 | 15 | 15 | 15 |
| y7 (1+) | 3.6 | 4.7 | 2.9 | 5.3 | 4.3 | 3.9 | 6.4 | 6.4 | 4.9 | 15 | 15 | 15 |
| y8 (1+) | 5.3 | 3.9 | 3.1 | 6.8 | 5 | 3.2 | 8.6 | 6.3 | 4.5 | 15 | 15 | 15 |
| y9 (1+) | 6.5 | 3.9 | 3.7 | 4.9 | 3.7 | 4.5 | 8.1 | 5.4 | 5.8 | 15 | 15 | 15 |
| y10 (1+) | 10.4 | 8.5 | 5.6 | 12.7 | 10.5 | 5.9 | 16.4 | 13.5 | 8.1 | 15 | 15 | 15 |
| sum | 3.3 | 1.8 | 2 | 4.9 | 2.5 | 2.9 | 5.9 | 3.1 | 3.5 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y3 (1+) | 8.7 | 7.2 | 6.2 | 9.9 | 7.6 | 7.2 | 13.2 | 10.5 | 9.5 | 15 | 15 | 15 |
| y4 (1+) | 6 | 8.8 | 5.9 | 6.5 | 10.2 | 7 | 8.8 | 13.5 | 9.2 | 15 | 15 | 15 |
| y5 (1+) | 7.2 | 3.6 | 3.2 | 7.9 | 3.5 | 3.7 | 10.7 | 5 | 4.9 | 15 | 15 | 15 |
| y6 (1+) | 11.7 | 6.3 | 7 | 15.4 | 6.3 | 7.3 | 19.3 | 8.9 | 10.1 | 15 | 15 | 15 |
| y7 (1+) | 8 | 3.4 | 1.9 | 7.8 | 3.8 | 2.6 | 11.2 | 5.1 | 3.2 | 15 | 15 | 15 |
| y8 (1+) | 5.1 | 3.4 | 2.3 | 6.5 | 4.1 | 4.4 | 8.3 | 5.3 | 5 | 15 | 15 | 15 |
| y9 (1+) | 11.6 | 7.9 | 7 | 9 | 9.4 | 5.8 | 14.7 | 12.3 | 9.1 | 15 | 15 | 15 |
| y10 (1+) | 9.6 | 7.8 | 6 | 8.1 | 9.2 | 7.7 | 12.6 | 12.1 | 9.8 | 15 | 15 | 15 |
| b4 (1+) | 19.9 | 11 | 6.2 | 20.1 | 11 | 5.7 | 28.3 | 15.6 | 8.4 | 15 | 15 | 15 |
| b3 (1+) | 5.8 | 3.6 | 4.6 | 4.6 | 4.2 | 5.4 | 7.4 | 5.5 | 7.1 | 15 | 15 | 15 |
| sum | 3.3 | 1.9 | 1.9 | 4 | 2.7 | 2.5 | 5.2 | 3.3 | 3.1 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y3 (1+) | 40.3 | 10.5 | 8.6 | 40.1 | 14.1 | 10.4 | 56.9 | 17.6 | 13.5 | 15 | 15 | 15 |
| y5 (1+) | 6.9 | 7.6 | 4.6 | 8.7 | 6.6 | 6.1 | 11.1 | 10.1 | 7.6 | 15 | 15 | 15 |
| y6 (1+) | 28 | 11.9 | 10.1 | 27.6 | 13.3 | 10.6 | 39.3 | 17.8 | 14.6 | 15 | 15 | 15 |
| y10 (1+) | 25.3 | 12.4 | 8.8 | 24.4 | 13.4 | 7.6 | 35.1 | 18.3 | 11.6 | 15 | 15 | 15 |
| b3 (1+) | 21.7 | 11.1 | 5.9 | 18.6 | 9.3 | 5.8 | 28.6 | 14.5 | 8.3 | 15 | 15 | 15 |
| sum | 7.3 | 4.7 | 3.7 | 7 | 5 | 4.5 | 10.1 | 6.9 | 5.8 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y5 (1+) | 14.8 | 6.2 | 4.5 | 12.6 | 5.9 | 3.8 | 19.4 | 8.6 | 5.9 | 15 | 15 | 15 |
| y6 (1+) | 3.4 | 3 | 3.1 | 5 | 3.5 | 3.1 | 6 | 4.6 | 4.4 | 15 | 15 | 15 |
| y9 (1+) | 5.1 | 4.3 | 3.1 | 6.5 | 4.9 | 4.3 | 8.3 | 6.5 | 5.3 | 15 | 15 | 15 |
| y10 (1+) | 5 | 3.4 | 1.8 | 4.3 | 3.9 | 1.9 | 6.6 | 5.2 | 2.6 | 15 | 15 | 15 |
| y11 (1+) | 8.8 | 4.2 | 3 | 9.6 | 5.5 | 3.4 | 13 | 6.9 | 4.5 | 15 | 15 | 15 |
| y12 (1+) | 13.4 | 8.8 | 5.3 | 10.4 | 9 | 4.9 | 17 | 12.6 | 7.2 | 15 | 15 | 15 |
| b4 (1+) | 13.2 | 6.8 | 7.2 | 13.7 | 8 | 8.3 | 19 | 10.5 | 11 | 15 | 15 | 15 |
| b3 (1+) | 12 | 4.1 | 4.3 | 14.4 | 8.4 | 5.5 | 18.7 | 9.3 | 7 | 15 | 15 | 15 |
| sum | 2.9 | 1.6 | 1.3 | 3.3 | 2.2 | 1.3 | 4.4 | 2.7 | 1.8 | 15 | 15 | 15 |
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