| Official Gene Symbol | Other Aliases |
|---|---|
| HADHB | N/A |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 474 | 51294 |
| Protein Name |
|---|
| Trifunctional enzyme subunit beta, mitochondrial |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MTILTYPFKN | LPTASKWALR | FSIRPLSCSS | QLRAAPAVQT | KTKKTLAKPN |
| 60 | 70 | 80 | 90 | 100 |
| IRNVVVVDGV | RTPFLLSGTS | YKDLMPHDLA | RAALTGLLHR | TSVPKEVVDY |
| 110 | 120 | 130 | 140 | 150 |
| IIFGTVIQEV | KTSNVAREAA | LGAGFSDKTP | AHTVTMACIS | ANQAMTTGVG |
| 160 | 170 | 180 | 190 | 200 |
| LIASGQCDVI | VAGGVELMSD | VPIRHSRKMR | KLMLDLNKAK | SMGQRLSLIS |
| 210 | 220 | 230 | 240 | 250 |
| KFRFNFLAPE | LPAVSEFSTS | ETMGHSADRL | AAAFAVSRLE | QDEYALRSHS |
| 260 | 270 | 280 | 290 | 300 |
| LAKKAQDEGL | LSDVVPFKVP | GKDTVTKDNG | IRPSSLEQMA | KLKPAFIKPY |
| 310 | 320 | 330 | 340 | 350 |
| GTVTAANSSF | LTDGASAMLI | MAEEKALAMG | YKPKAYLRDF | MYVSQDPKDQ |
| 360 | 370 | 380 | 390 | 400 |
| LLLGPTYATP | KVLEKAGLTM | NDIDAFEFHE | AFSGQILANF | KAMDSDWFAE |
| 410 | 420 | 430 | 440 | 450 |
| NYMGRKTKVG | LPPLEKFNNW | GGSLSLGHPF | GATGCRLVMA | AANRLRKEGG |
| 460 | 470 | 474 | ||
| QYGLVAACAA | GGQGHAMIVE | AYPK |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b2 (1+) | 5.6 | 5.5 | 5.2 | 5 | 6.2 | 5.1 | 7.5 | 8.3 | 7.3 | 16 | 16 | 17 |
| y4 (1+) | 9.1 | 2.8 | 5.2 | 13 | 6.2 | 5.7 | 15.9 | 6.8 | 7.7 | 16 | 16 | 17 |
| y6 (1+) | 7.8 | 4.8 | 3.9 | 5.8 | 2.8 | 4.9 | 9.7 | 5.6 | 6.3 | 16 | 16 | 17 |
| y7 (1+) | 7.7 | 3.7 | 3.1 | 7.2 | 4.3 | 3.5 | 10.5 | 5.7 | 4.7 | 16 | 16 | 17 |
| y7 (2+) | 12.8 | 4.3 | 3.8 | 13.7 | 5.7 | 3.4 | 18.7 | 7.1 | 5.1 | 16 | 16 | 17 |
| sum | 3.8 | 2.3 | 2.1 | 3.5 | 2.4 | 2.2 | 5.2 | 3.3 | 3 | 16 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b2 (1+) | 7.3 | 2.8 | 3.7 | 9.4 | 0.4 |
| y4 (1+) | 5.8 | 2.8 | 10.5 | 6.6 | 1.4 |
| y6 (1+) | 6.5 | 3.1 | 2.4 | 9.1 | 5.3 |
| y7 (1+) | 5.7 | 3.7 | 5 | 5.5 | 2.6 |
| y7 (2+) | 4.6 | 5.7 | 3.4 | 4.1 | 8 |
| sum | 2.8 | 0.5 | 2.8 | 3.4 | 2.8 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b2 (1+) | 4.4 | 5.2 |
| y4 (1+) | 5 | 7.6 |
| y6 (1+) | 4.9 | 4.1 |
| y7 (1+) | 4.3 | 4.3 |
| y7 (2+) | 5.3 | 3.4 |
| sum | 2.1 | 2.7 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b2 (1+) | 13.2 | 25.8 | 29 |
| y4 (1+) | 4 | 22.5 | 22.9 |
| y6 (1+) | 3.9 | 23.9 | 24.2 |
| y7 (1+) | 20 | 21 | 29 |
| y7 (2+) | 10 | 39.8 | 41 |
| sum | 0.1 | 20.9 | 20.9 |
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