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Overview Data source: UniProt

Official Gene Symbol Other Aliases
TAB1 MAP3K7IP1
Sequence Length (AA) Molecular Weight (Da)
504 54644
Protein Name
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MAAQRRSLLQ SEQQPSWTDD LPLCHLSGVG SASNRSYSAD GKGTESHPPE
60 70 80 90 100
DSWLKFRSEN NCFLYGVFNG YDGNRVTNFV AQRLSAELLL GQLNAEHAEA
110 120 130 140 150
DVRRVLLQAF DVVERSFLES IDDALAEKAS LQSQLPEGVP QHQLPPQYQK
160 170 180 190 200
ILERLKTLER EISGGAMAVV AVLLNNKLYV ANVGTNRALL CKSTVDGLQV
210 220 230 240 250
TQLNVDHTTE NEDELFRLSQ LGLDAGKIKQ VGIICGQEST RRIGDYKVKY
260 270 280 290 300
GYTDIDLLSA AKSKPIIAEP EIHGAQPLDG VTGFLVLMSE GLYKALEAAH
310 320 330 340 350
GPGQANQEIA AMIDTEFAKQ TSLDAVAQAV VDRVKRIHSD TFASGGERAR
360 370 380 390 400
FCPRHEDMTL LVRNFGYPLG EMSQPTPSPA PAAGGRVYPV SVPYSSAQST
410 420 430 440 450
SKTSVTLSLV MPSQGQMVNG AHSASTLDEA TPTLTNQSPT LTLQSTNTHT
460 470 480 490 500
QSSSSSSDGG LFRSRPAHSL PPGEDGRVEP YVDFAEFYRL WSVDHGEQSV
504
VTAP

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-906 Collapse assay details

Data source: Panorama

Official Gene Symbol
TAB1
Peptide Sequence
GTESHPPEDSWLK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
43
Peptide End
55
CPTAC ID
CPTAC-906
Peptide Molecular Mass
1,481.6787
Species
Homo sapiens (Human)
Assay Type
Direct PRM
Matrix
Pooled patient derived xenograft breast tumor digest
Submitting Laboratory
Washington University in St. Louis
Submitting Lab PI
Reid Townsend

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TripleTOF 5600+ (SCIEX)
Internal Standard
Peptide
Peptide Standard Purity
Crude
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
2DPlus nano-LC (Eksigent)
Column Packing
ChromXP C18-CL, 3 µm, 120 Å
Column Dimensions
200 µm x 15 cm
Flow Rate
800 nL/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y3 (1+) 37 22 18.8 35.1 24 27.9 51 32.6 33.6 15 15 15
y4 (1+) 29.5 9.1 6.1 28.9 8.3 7.5 41.3 12.3 9.7 15 15 15
y7 (1+) 12.2 3.3 4.1 15.6 3.7 5.6 19.8 5 6.9 15 15 15
y8 (1+) 10.2 6.6 5.5 9.9 6.9 6 14.2 9.5 8.1 15 15 15
sum 7.2 5.2 3.9 7.7 5.6 4.1 10.5 7.6 5.7 15 15 15

Additional Resources and Comments


Assay Details for CPTAC-907 Collapse assay details

Data source: Panorama

Official Gene Symbol
TAB1
Peptide Modified Sequence
QVGIIC[+57.0]GQESTR
Modification Type
Carbamidomethyl Cysteine
Protein - Site of Modification
235
Peptide - Site of Modification
6
Peptide Start
230
Peptide End
241
CPTAC ID
CPTAC-907
Peptide Molecular Mass
1,346.6612
Species
Homo sapiens (Human)
Assay Type
Direct PRM
Matrix
Pooled patient derived xenograft breast tumor digest
Submitting Laboratory
Washington University in St. Louis
Submitting Lab PI
Reid Townsend

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TripleTOF 5600+ (SCIEX)
Internal Standard
Peptide
Peptide Standard Purity
Crude
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
2DPlus nano-LC (Eksigent)
Column Packing
ChromXP C18-CL, 3 µm, 120 Å
Column Dimensions
200 µm x 15 cm
Flow Rate
800 nL/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

Loader

Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y3 (1+) 25 4.5 5.7 19.7 5 5.5 31.8 6.7 7.9 15 15 15
y6 (1+) 13 6.1 4.7 13.6 7.2 6.9 18.8 9.4 8.3 15 15 15
y7 (1+) 5.4 4.1 2.6 6.4 5.3 4 8.4 6.7 4.8 15 15 15
y8 (1+) 7.4 3 4 11.5 2.9 4.1 13.7 4.2 5.7 15 15 15
y9 (1+) 18.7 10.1 10.5 19.8 10.2 12.3 27.2 14.4 16.2 15 15 15
y10 (1+) 6.6 6.3 2.4 6.2 5.7 3.1 9.1 8.5 3.9 15 15 15
b3 (1+) 17.7 14.2 7.8 19.4 14.1 8.1 26.3 20 11.2 15 15 15
sum 4.2 2.8 1.7 4.4 2.8 2.3 6.1 4 2.9 15 15 15

Additional Resources and Comments