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Please include the following statement when referencing the CPTAC Assay Portal
We would like to acknowledge the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (assays.cancer.gov) for developing assays and establishing criteria for the assays described in this publication.

Abca6

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Available Assays

Overview Data source: UniProt

Official Gene Symbol Other Aliases
Abca6 N/A
Sequence Length (AA) Molecular Weight (Da)
1624 183283
Protein Name
ATP-binding cassette sub-family A member 6
Sources
UniProt
PhosphoSitePlus ®
GeneCards 		Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MKELSVHVRQ QTRALLHKIL LKKWRRKRES LLEWSIPIII GLHMGLFSYL
60 70 80 90 100
ARNIQVLEVP PQDLGSLNEF NGSSLVVVYT PISNITQQIM NKTTFAPTMK
110 120 130 140 150
GTRIIGVPSI EDLDEVLLHN IPDALGVIFN DSFSYQLKVL RMYGNPFLKE
160 170 180 190 200
DLLAHCWDTH SQAFCSLSKY WERGFVALQT AINAGIIEVT TNHSVMEELM
210 220 230 240 250
SIDGINMKTL PFIPRDLSDY EIFILFCLLY FSSFIYFASS NVTKERKQCK
260 270 280 290 300
EVMKVMGLQD SAFWLSWGLI YVGFIFIISI FIAIIITSTQ IIMMTGFLVI
310 320 330 340 350
FTLFFLYGLS LIAVTFLMAV LLQKAVLTNL IVLFFTLFWG CVGFTVLHKE
360 370 380 390 400
LPPSLEWVLS IFSPFAFTSG MAKVIFQDYN LNGVVFPDPS GESYVMIAVF
410 420 430 440 450
FILAFDSLLY LVLALYFDKI LLYGAEHRSA PLFFLNPTSC FRKTANRNKV
460 470 480 490 500
IERDLDPELP SDEYFEPVDP EYQGKEAIRI RNIKKEYKGK SGKVKALKGL
510 520 530 540 550
FLDIYESQIT AILGHSGAGK SSLLNILSGL YVPTAGSVTV YNKNLSDMQD
560 570 580 590 600
LKEIRKAIGV CPQHNVQFDA LTVKENLTLF AKIKGILPQD VEQEVQQILS
610 620 630 640 650
ELDMQNIRDD LAEHLSEGQK RKLTFGIATV GDPQILLLDE PTVGLDPFSR
660 670 680 690 700
QRIWGFLKER RADHVILFST QFMDEADILA DRKVLIANGA LKCTGSSVFL
710 720 730 740 750
KRKWGLGYHL SLFMDETCDS ERLTSFINHH IPYAKLKAKT KEKLVYILPL
760 770 780 790 800
ERTSEFPEFF SDLDKYSGQG LMSYEVSMST LNDVFLNLEG EPSTKQDFEK
810 820 830 840 850
RETATDSESL NDMEVAYPSL SQVQETVSTM SLWRMQVCAI ARLRILKLKR
860 870 880 890 900
ERKAFLIILL LLGIALLPLV IEYVANALLE VKNNWEFKTD LYFLSPGQLP
910 920 930 940 950
QGLRTSLLVI NNTESNIEDF LQSLKHQNIV LEVDDFENRN ATNSLSYNGA
960 970 980 990 1000
IIVSGRQKDY RFSAVCNTKR LHCFPILMNV ISNGILHMLN HTQYIRIKED
1010 1020 1030 1040 1050
IFSPFIVLVW TGIQETCLFI LCVICSLSPH IAMSSVSDYK KKADSQLWIS
1060 1070 1080 1090 1100
GLYPSAYWCG QAVVDISLFS GMLLTSYFTS YTSKLLNIDM TSEIVFSVIV
1110 1120 1130 1140 1150
LALGCAASLV FLTYVISFVF GKRKKNSTLW SICFLLVIAI TFEKVANGPF
1160 1170 1180 1190 1200
NEALVISATM LVPSFALNGL LVVLEMRAYQ YYIEFEEIKH GLSAVDLLLC
1210 1220 1230 1240 1250
LIPYIHTLLF IFVLRCLELK YGKNVVRRDP IFRIAPQSLK AQPNPEEPID
1260 1270 1280 1290 1300
EDENVQAERL RTSDALSTPN LDEKPVIIAS CLHKEYAGQK KHCCSRRTRN
1310 1320 1330 1340 1350
MAVRNVSFCV NKGEILGLLG PDGAGKSSSI RMIAGITKPT AGQVELKRLS
1360 1370 1380 1390 1400
SAVGHQGDSR AEFGYCPQEN GLWPNLTVKE HLELYAAVKG LRKEDAVVAI
1410 1420 1430 1440 1450
SRLVNALKLH DQLNVQVQNL VAGATRKLCF VLSILGNSPV LILDEPSTGL
1460 1470 1480 1490 1500
DVSGKHQVWQ AIQAVVKDNE KGVLLSTHDL AEAEALCDRA AIMVSGRLRC
1510 1520 1530 1540 1550
IGPIQHLKRK FGQDYVLELR VKDVSQEPLV HREILKLFPQ AARQDRCFSL
1560 1570 1580 1590 1600
LTYKLPVTDV HPLSQAFHKL EAVKHGFDLE DYSLSQCTLD RVILELSKEQ
1610 1620 1624
ELGTVYEEAD MTLGRKLLPP SDEL

Data source: UniProt

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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All other points link out to UniProt


Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for non-CPTAC-3441 Collapse assay details

Data source: Panorama

Official Gene Symbol
Abca6
Peptide Sequence
ELSVHVR
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
3
Peptide End
9
CPTAC ID
non-CPTAC-3441
Peptide Molecular Mass
838.4661
Species
Mus musculus (Mouse)
Assay Type
Direct MRM
Matrix
Plasma
Submitting Laboratory
UVic-Genome BC Proteomics Centre
Submitting Lab PI
Christoph Borchers

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
Agilent 6490/6495 QQQ
Internal Standard
synthetic peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
1290 LC (Agilent)
Column Packing
Zorbax Eclipse Plus C18, 1.8 µm
Column Dimensions
2.1 x 150 mm
Flow Rate
400 µL/min

Chromatograms

Data source: Panorama

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Response Curves

Data source: Panorama

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Retrieving Data

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Repeatability

Data source: Panorama

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  Average intra-assay CV
(within day CV)		 Average inter-assay CV
(between day CV)		 Total CV
equation		 n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y5 (1+) 10.7 3.9 4.2 14.6 6.9 7.9 18.1 7.9 8.9 15 15 15
y5 (2+) 16.3 5.6 10 17.4 7.4 11.7 23.8 9.3 15.4 15 15 15
y3 (2+) 20.2 11.7 14.7 22 12.2 11.5 29.9 16.9 18.7 15 15 15
b4 (2+) 10 8.4 5.5 12.1 8.8 8.8 15.7 12.2 10.4 15 15 15
sum 6.7 3.9 2.8 10.7 5.2 5.6 12.6 6.5 6.3 15 15 15

Additional Resources and Comments

Resources
Download SOPs
View Peptide in Panorama
View Protein in Panorama
Comments