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Please include the following statement when referencing the CPTAC Assay Portal
We would like to acknowledge the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (assays.cancer.gov) for developing assays and establishing criteria for the assays described in this publication.

Mmrn2

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Available Assays

Overview Data source: UniProt

Official Gene Symbol Other Aliases
Mmrn2 N/A
Sequence Length (AA) Molecular Weight (Da)
943 105206
Protein Name
Multimerin-2
Sources
UniProt
PhosphoSitePlus ®
GeneCards 		Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MIPTLLLGFG VYLSWGLLGS WAQDPGTKFS HLNRPGMPEG WRLGAEDTSR
60 70 80 90 100
DPIRRNWCPY QKSRLVTFVA ACKTEKFLVH SQQPCPQGAP DCQGVRVMYR
110 120 130 140 150
VAQKPVYQVQ QKVLISVDWR CCPGFQGPDC QDHNPTANPE PTEPSGKLQE
160 170 180 190 200
TWDSMDGFEL GHPVPEFNEI KVPQEQQENL LQNLQNDAQS VEDGFPGSWE
210 220 230 240 250
APPSNLTDEM TEANLTEFEF PGRTSEHLLQ PHIDAFLKAH FSPIWKNFND
260 270 280 290 300
SLHSLSQAIR NLSLDVEANH QAIKMIQEGT VARADFQELG AKFEAKVQQN
310 320 330 340 350
SQRLGQLWQD VEDQLHAQRR SVHHALSDVQ AEVSTKLKQL VKAQELPGAN
360 370 380 390 400
GSLVMASAAA AARPEPESLQ ARLGQLQRNL SALHMVTSQR EEELQSTLKN
410 420 430 440 450
MDSVLKQHAE EIKELYSESD ETFDQISKVE RQVEELLVNH TGLRELRVIL
460 470 480 490 500
MEKSLIMEEN KEEIERQLLE LNLTLQHLHA GHADLIKYVK DCNCQRVNSD
510 520 530 540 550
VDVAPEGHRD VMHTLEETQV SLDEQHQLDG SSLQALQSTV DAMSSAMDAY
560 570 580 590 600
RGEGERARAE RARIRSQLRA LDHAVEALKT AANGTRKEIR LLHGSFTALL
610 620 630 640 650
EDALRHQAVL AALFGEEMID EMSEEAPRPL PLDYEQIRLA LQDAASGLQE
660 670 680 690 700
QAIGWEDLAT RVEALEKAAG GFVEQHPQLA EGLEPSHDSG REEEAMTLAE
710 720 730 740 750
LEQEIRRLSS DVKQIGQCCE ASWAASLNSS LEDLHSMLLD TQHGLRQHRQ
760 770 780 790 800
LFHNLFQNFQ GLVASNISLD LGKLQAMLSK KDKKQPRGPG ESRKRDKKQV
810 820 830 840 850
VMSTDAHAKG LELWETGSPV AFYAGSSEGA TALQMVKFNT TSINVGSSYF
860 870 880 890 900
PEHGYFRAPK RGVYLFAVSI TFGPGPGMGQ LVFEGHHRVP VYSTEQRGGS
910 920 930 940 943
TATTFAMVEL QKGERAWFEL IQGSATKGSQ PGTAFGGFLM FKT

Data source: UniProt

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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All other points link out to UniProt


Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for non-CPTAC-3482 Collapse assay details

Data source: Panorama

Official Gene Symbol
Mmrn2
Peptide Sequence
VPVYSTEQR
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
889
Peptide End
897
CPTAC ID
non-CPTAC-3482
Peptide Molecular Mass
1,077.5455
Species
Mus musculus (Mouse)
Assay Type
Direct MRM
Matrix
Plasma
Submitting Laboratory
UVic-Genome BC Proteomics Centre
Submitting Lab PI
Christoph Borchers

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
Agilent 6490/6495 QQQ
Internal Standard
synthetic peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
1290 LC (Agilent)
Column Packing
Zorbax Eclipse Plus C18, 1.8 µm
Column Dimensions
2.1 x 150 mm
Flow Rate
400 µL/min

Chromatograms

Data source: Panorama

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Response Curves

Data source: Panorama

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Retrieving Data

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Repeatability

Data source: Panorama

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  Average intra-assay CV
(within day CV)		 Average inter-assay CV
(between day CV)		 Total CV
equation		 n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y8 (2+) 10.3 3.5 4.2 9.8 4.5 6.1 14.2 5.7 7.4 15 15 15
y2 (1+) 13.8 5.6 5.6 15 6.1 5.2 20.4 8.3 7.6 15 15 15
y5 (1+) 13.3 7.1 4.1 12.3 8.6 7.6 18.1 11.2 8.6 15 15 15
y6 (1+) 6.1 6.4 3.5 8.9 5.6 5.2 10.8 8.5 6.3 15 15 15
y7 (1+) 6.6 7.7 5.6 13.5 7.8 7.7 15 11 9.5 15 15 15
sum 4.5 2.3 2.8 6.8 3.9 5.3 8.2 4.5 6 15 15 15

Additional Resources and Comments

Resources
Download SOPs
View Peptide in Panorama
View Protein in Panorama
Comments