| Official Gene Symbol | Other Aliases |
|---|---|
| ARHGAP1 | CDC42GAP, RHOGAP1 |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 439 | 50436 |
| Protein Name |
|---|
| Rho GTPase-activating protein 1 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MDPLSELQDD | LTLDDTSEAL | NQLKLASIDE | KNWPSDEMPD | FPKSDDSKSS |
| 60 | 70 | 80 | 90 | 100 |
| SPELVTHLKW | DDPYYDIARH | QIVEVAGDDK | YGRKIIVFSA | CRMPPSHQLD |
| 110 | 120 | 130 | 140 | 150 |
| HSKLLGYLKH | TLDQYVESDY | TLLYLHHGLT | SDNKPSLSWL | RDAYREFDRK |
| 160 | 170 | 180 | 190 | 200 |
| YKKNIKALYI | VHPTMFIKTL | LILFKPLISF | KFGQKIFYVN | YLSELSEHVK |
| 210 | 220 | 230 | 240 | 250 |
| LEQLGIPRQV | LKYDDFLKST | QKSPATAPKP | MPPRPPLPNQ | QFGVSLQHLQ |
| 260 | 270 | 280 | 290 | 300 |
| EKNPEQEPIP | IVLRETVAYL | QAHALTTEGI | FRRSANTQVV | REVQQKYNMG |
| 310 | 320 | 330 | 340 | 350 |
| LPVDFDQYNE | LHLPAVILKT | FLRELPEPLL | TFDLYPHVVG | FLNIDESQRV |
| 360 | 370 | 380 | 390 | 400 |
| PATLQVLQTL | PEENYQVLRF | LTAFLVQISA | HSDQNKMTNT | NLAVVFGPNL |
| 410 | 420 | 430 | 439 | |
| LWAKDAAITL | KAINPINTFT | KFLLDHQGEL | FPSPDPSGL |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
loading
Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b3 (1+) | 8.5 | 4.5 | 4 | 8.2 | 4.2 | 3.9 | 11.8 | 6.2 | 5.6 | 16 | 16 | 17 |
| y7 (1+) | 4.8 | 4 | 6.1 | 6.6 | 3.8 | 6 | 8.2 | 5.5 | 8.6 | 16 | 16 | 17 |
| y8 (1+) | 8.2 | 3 | 5 | 9.2 | 4.9 | 4.9 | 12.3 | 5.7 | 7 | 16 | 16 | 17 |
| y7 (2+) | 6.8 | 4.6 | 9.2 | 8.3 | 4.6 | 6.8 | 10.7 | 6.5 | 11.4 | 16 | 16 | 17 |
| y8 (2+) | 5.6 | 5.9 | 6 | 5.4 | 6 | 8.4 | 7.8 | 8.4 | 10.3 | 16 | 16 | 17 |
| sum | 3 | 2.4 | 2.2 | 2.9 | 2.2 | 3.3 | 4.2 | 3.3 | 4 | 16 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b3 (1+) | 8.2 | 9 | 3.5 | 13.2 | 9 |
| y7 (1+) | 9.1 | 4.3 | 5.9 | 8.8 | 7 |
| y8 (1+) | 7.6 | 3.6 | 7.8 | 9.6 | 3 |
| y7 (2+) | 9.2 | 9.8 | 3.9 | 4.7 | 4.5 |
| y8 (2+) | 12.1 | 8.3 | 5.7 | 11.9 | 3.8 |
| sum | 3.3 | 1.6 | 1.9 | 1.6 | 1.9 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b3 (1+) | 8.7 | 6 |
| y7 (1+) | 6.6 | 5.8 |
| y8 (1+) | 5.9 | 7.1 |
| y7 (2+) | 7 | 5.4 |
| y8 (2+) | 8.4 | 7.9 |
| sum | 2 | 2.1 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b3 (1+) | 2.4 | 23.4 | 23.5 |
| y7 (1+) | 20.4 | 22.1 | 30.1 |
| y8 (1+) | 3.6 | 28.1 | 28.3 |
| y7 (2+) | 5 | 40.7 | 41 |
| y8 (2+) | 17.2 | 13.8 | 22.1 |
| sum | 9.8 | 20.2 | 22.5 |
Comments