| Official Gene Symbol | Other Aliases |
|---|---|
| ARPC4 | ARC20 |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 168 | 19667 |
| Protein Name |
|---|
| Actin-related protein 2/3 complex subunit 4 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MTATLRPYLS | AVRATLQAAL | CLENFSSQVV | ERHNKPEVEV | RSSKELLLQP |
| 60 | 70 | 80 | 90 | 100 |
| VTISRNEKEK | VLIEGSINSV | RVSIAVKQAD | EIEKILCHKF | MRFMMMRAEN |
| 110 | 120 | 130 | 140 | 150 |
| FFILRRKPVE | GYDISFLITN | FHTEQMYKHK | LVDFVIHFME | EIDKEISEMK |
| 160 | 168 | |||
| LSVNARARIV | AEEFLKNF |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b2 (1+) | 10.2 | 3.2 | 10.1 | 12 | 4.6 | 11 | 15.7 | 5.6 | 14.9 | 16 | 16 | 17 |
| y7 (1+) | 8.2 | 9.3 | 6.4 | 9.6 | 8.9 | 5.1 | 12.6 | 12.9 | 8.2 | 16 | 16 | 17 |
| y8 (1+) | 10.6 | 6 | 8.6 | 9.3 | 6.1 | 7.8 | 14.1 | 8.6 | 11.6 | 16 | 16 | 17 |
| y9 (1+) | 15.9 | 5.7 | 7.7 | 14.5 | 10.1 | 7.3 | 21.5 | 11.6 | 10.6 | 16 | 16 | 17 |
| y9 (2+) | 8.3 | 12.3 | 10 | 9.4 | 12.9 | 9 | 12.5 | 17.8 | 13.5 | 16 | 16 | 17 |
| sum | 6.6 | 4 | 2.3 | 4.9 | 4 | 3.1 | 8.2 | 5.7 | 3.9 | 16 | 16 | 17 |
Data source: Panorama
| Fragment ion / Transition | control_intra_CV | actual_temp_intra_CV | frozen_intra_CV | FTx1_intra_CV | FTx2_intra_CV |
|---|---|---|---|---|---|
| b2 (1+) | 5.7 | 5.8 | 13.3 | 3.3 | 2.7 |
| y7 (1+) | 6.8 | 5.8 | 3.8 | 6.4 | 15.5 |
| y8 (1+) | 5.1 | 8.5 | 1.8 | 7.7 | 6.3 |
| y9 (1+) | 6.6 | 13.6 | 8.3 | 8 | 12.4 |
| y9 (2+) | 7.9 | 3.3 | 11.2 | 17.2 | 9 |
| sum | 2.3 | 3.1 | 1.1 | 4 | 4.2 |
| Fragment ion / Transition | all_intra_CV | all_inter_CV |
|---|---|---|
| b2 (1+) | 6.1 | 8.1 |
| y7 (1+) | 7.3 | 5.3 |
| y8 (1+) | 6.3 | 5.9 |
| y9 (1+) | 10.4 | 9.7 |
| y9 (2+) | 8.7 | 8.5 |
| sum | 3 | 2.6 |
Data source: Panorama
| Fragment ion / Transition | intra_CV | inter_CV | total_CV |
|---|---|---|---|
| b2 (1+) | 3.4 | 18 | 18.3 |
| y7 (1+) | 5.5 | 24.2 | 24.8 |
| y8 (1+) | 6.3 | 19 | 20 |
| y9 (1+) | 1.2 | 25 | 25 |
| y9 (2+) | 4.4 | 13.9 | 14.6 |
| sum | 3.1 | 18.4 | 18.7 |
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