Paics, CPTAC-3741 - CPTAC Assay Portal | Office of Cancer Clinical Proteomics Research

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Overview Data source: UniProt

Official Gene Symbol	Other Aliases
Paics	N/A

Sequence Length (AA)	Molecular Weight (Da)
425	47006

Protein Name
Multifunctional protein ADE2

Sources
UniProt PhosphoSitePlus ® GeneCards	Human Protein Atlas

Protein Sequence hover to view complete sequence

10	20	30	40	50
MATAVVVNIG	KKLYEGKTKE	VYELLDTPGR	VLLQSKDQIT	AGNAARKNHL
60	70	80	90	100
EGKAAISNKI	TSCIFQLLQE	AGIKTAFTKK	CGETAFIAPQ	CEMIPIEWVC
110	120	130	140	150
RRIATGSFLK	RNPGVQEGYK	FYPPKVEMFF	KDDANNDPQW	SEEQLIAAKF
160	170	180	190	200
CFAGLVIGQT	EVDIMSHATQ	AIFEILEKSW	LPQDCTLVDM	KIEFGVDVTT
210	220	230	240	250
KEIVLADVID	NDSWRLWPSG	DRSQQKDKQS	YRDLKEVTPE	GLQMVKKNFE
260	270	280	290	300
WVADRVELLL	KSDSQCRVVV	LMGSTSDLGH	CEKIKKACGN	FGIPCELRVT
310	320	330	340	350
SAHKGPDETL	RIKAEYEGDG	IPTVFVSVAG	RSNGLGPVLS	GNTAYPVISC
360	370	380	390	400
PPITPDWGAQ	DVWSSLRLPS	GIGCSTILSP	EGSAQFAAQI	FGLNNHLVWA
410	420	425
KLRASILNTW	ISLKQADKKV	RQCNL

Data source: UniProt

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Assay Details for non-CPTAC-3741 Collapse assay details

Data source: Panorama

Official Gene Symbol: Paics
Peptide Sequence: DQITAGNAAR
Modification Type: unmodified
Protein - Site of Modification: N/A
Peptide - Site of Modification: N/A
Peptide Start: 37
Peptide End: 46

CPTAC ID: non-CPTAC-3741
Peptide Molecular Mass: 1,015.5047
Species: Mus musculus (Mouse)
Assay Type: Direct MRM
Matrix: Plasma
Submitting Laboratory: UVic-Genome BC Proteomics Centre
Submitting Lab PI: Christoph Borchers

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument: Agilent 6490/6495 QQQ
Internal Standard: synthetic peptide
Peptide Standard Purity: >95%
Peptide Standard Label Type: 13C and 15N at C-terminus R

LC: 1290 LC (Agilent)
Column Packing: Zorbax Eclipse Plus C18, 1.8 µm
Column Dimensions: 2.1 x 150 mm
Flow Rate: 400 µL/min

Chromatograms

Data source: Panorama

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Response Curves

Data source: Panorama

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Retrieving Data

Repeatability

Data source: Panorama

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	Average intra-assay CV (within day CV)			Average inter-assay CV (between day CV)			Total CV			n=
Fragment ion / Transition	Low	Med	High	Low	Med	High	Low	Med	High	Low	Med	High
b3 (1+)	13.6	9.5	7.7	13.2	10.3	10.7	19	14	13.2	15	15	15
b2 (1+)	4.9	5.9	6.3	7	7	8.3	8.5	9.2	10.4	15	15	15
y5 (1+)	13.4	10.4	10.5	18.6	20.7	17.4	22.9	23.2	20.3	15	15	15
y7 (1+)	7.9	6.7	7.8	5.9	8.6	10.2	9.9	10.9	12.8	15	15	15
y8 (1+)	10.3	7.1	8.5	12.2	8.1	11	16	10.8	13.9	15	15	15
sum	2.8	3.4	4.9	3.2	5.7	7.7	4.3	6.6	9.1	15	15	15

Paics

Overview Data source: UniProt

Protein Sequence hover to view complete sequence

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Assay Details for non-CPTAC-3741 Collapse assay details

Assay Parameters Collapse assay parameters

Chromatograms

Response Curves

Repeatability

Additional Resources and Comments

Comments

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Paics

Overview Data source: UniProt

Protein Sequence hover to view complete sequence

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Assay Details for non-CPTAC-3741 Collapse assay details

Assay Parameters Collapse assay parameters

Chromatograms

Response Curves

Repeatability

Additional Resources and Comments

Comments