Show Nav →
Please include the following statement when referencing the CPTAC Assay Portal
We would like to acknowledge the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (assays.cancer.gov) for developing assays and establishing criteria for the assays described in this publication.

Ltbp2

Previous Assay Next Assay
Available Assays

Overview Data source: UniProt

Official Gene Symbol Other Aliases
Ltbp2 N/A
Sequence Length (AA) Molecular Weight (Da)
1813 195829
Protein Name
Latent-transforming growth factor beta-binding protein 2
Sources
UniProt
PhosphoSitePlus ®
GeneCards 		Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MRAPTTARCS GCIQRVRWRG FLPLVLAVLM GTSHAQRDSI GRYEPASRDA
60 70 80 90 100
NRLWHPVGSH PAAAAAKVYS LFREPDAPVP GLSPSEWNQP AQGNPGWLAE
110 120 130 140 150
AEARRPPRTQ QLRRVQPPVQ TRRSHPRGQQ QIAARAAPSV ARLETPQRPA
160 170 180 190 200
AARRGRLTGR NVCGGQCCPG WTTSNSTNHC IKPVCQPPCQ NRGSCSRPQV
210 220 230 240 250
CICRSGFRGA RCEEVIPEEE FDPQNARPVP RRSVERAPGP HRSSEARGSL
260 270 280 290 300
VTRIQPLVPP PSPPPSRRLS QPWPLQQHSG PSRTVRRYPA TGANGQLMSN
310 320 330 340 350
ALPSGLELRD SSPQAAHVNH LSPPWGLNLT EKIKKIKVVF TPTICKQTCA
360 370 380 390 400
RGRCANSCEK GDTTTLYSQG GHGHDPKSGF RIYFCQIPCL NGGRCIGRDE
410 420 430 440 450
CWCPANSTGK FCHLPVPQPD REPAGRGSRH RTLLEGPLKQ STFTLPLSNQ
460 470 480 490 500
LASVNPSLVK VQIHHPPEAS VQIHQVARVR GELDPVLEDN SVETRASHRP
510 520 530 540 550
HGNLGHSPWA SNSIPARAGE APRPPPVLSR HYGLLGQCYL STVNGQCANP
560 570 580 590 600
LGSLTSQEDC CGSVGTFWGV TSCAPCPPRQ EGPAFPVIEN GQLECPQGYK
610 620 630 640 650
RLNLSHCQDI NECLTLGLCK DSECVNTRGS YLCTCRPGLM LDPSRSRCVS
660 670 680 690 700
DKAVSMQQGL CYRSLGSGTC TLPLVHRITK QICCCSRVGK AWGSTCEQCP
710 720 730 740 750
LPGTEAFREI CPAGHGYTYS SSDIRLSMRK AEEEELASPL REQTEQSTAP
760 770 780 790 800
PPGQAERQPL RAATATWIEA ETLPDKGDSR AVQITTSAPH LPARVPGDAT
810 820 830 840 850
GRPAPSLPGQ GIPESPAEEQ VIPSSDVLVT HSPPDFDPCF AGASNICGPG
860 870 880 890 900
TCVSLPNGYR CVCSPGYQLH PSQDYCTDDN ECMRNPCEGR GRCVNSVGSY
910 920 930 940 950
SCLCYPGYTL VTLGDTQECQ DIDECEQPGV CSGGRCSNTE GSYHCECDRG
960 970 980 990 1000
YIMVRKGHCQ DINECRHPGT CPDGRCVNSP GSYTCLACEE GYVGQSGSCV
1010 1020 1030 1040 1050
DVNECLTPGI CTHGRCINME GSFRCSCEPG YEVTPDKKGC RDVDECASRA
1060 1070 1080 1090 1100
SCPTGLCLNT EGSFTCSACQ SGYWVNEDGT ACEDLDECAF PGVCPTGVCT
1110 1120 1130 1140 1150
NTVGSFSCKD CDQGYRPNPL GNRCEDVDEC EGPQSSCRGG ECKNTEGSYQ
1160 1170 1180 1190 1200
CLCHQGFQLV NGTMCEDVNE CVGEEHCAPH GECLNSLGSF FCLCAPGFAS
1210 1220 1230 1240 1250
AEGGTRCQDV DECAATDPCP GGHCVNTEGS FSCLCETASF QPSPDSGECL
1260 1270 1280 1290 1300
DIDECEDRED PVCGAWRCEN SPGSYRCILD CQPGFYVAPN GDCIDIDECA
1310 1320 1330 1340 1350
NDTVCGNHGF CDNTDGSFRC LCDQGFETSP SGWECVDVNE CELMMAVCGD
1360 1370 1380 1390 1400
ALCENVEGSF LCLCASDLEE YDAEEGHCRP RVAGAQRIPE VRTEDQAPSL
1410 1420 1430 1440 1450
IRMECYSEHN GGPPCSQILG QNSTQAECCC TQGARWGKAC APCPSEDSVE
1460 1470 1480 1490 1500
FSQLCPSGQG YIPVEGAWTF GQTMYTDADE CVLFGPALCQ NGRCSNIVPG
1510 1520 1530 1540 1550
YICLCNPGYH YDASSRKCQD HNECQDLACE NGECVNQEGS FHCLCNPPLT
1560 1570 1580 1590 1600
LDLSGQRCVN TTSSTEDFPD HDIHMDICWK KVTNDVCSQP LRGHHTTYTE
1610 1620 1630 1640 1650
CCCQDGEAWS QQCALCPPRS SEVYAQLCNV ARIEAERGAG IHFRPGYEYG
1660 1670 1680 1690 1700
PGLDDLPENL YGPDGAPFYN YLGPEDTAPE PPFSNPASQP GDNTPVLEPP
1710 1720 1730 1740 1750
LQPSELQPHY LASHSEPPAS FEGLQAEECG ILNGCENGRC VRVREGYTCD
1760 1770 1780 1790 1800
CFEGFQLDAP TLACVDVNEC EDLNGPARLC AHGHCENTEG SYRCHCSPGY
1810 1813
VAEPGPPHCA AKE

Data source: UniProt

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

Click a point on a node
to view detailed assay information below
All other points link out to UniProt


Phosphorylation Acetylation Ubiquitylation Other

loading

Loader

Assay Details for non-CPTAC-3989 Collapse assay details

Data source: Panorama

Official Gene Symbol
Ltbp2
Peptide Sequence
TLLEGPLK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
432
Peptide End
439
CPTAC ID
non-CPTAC-3989
Peptide Molecular Mass
869.5222
Species
Mus musculus (Mouse)
Assay Type
Direct MRM
Matrix
Plasma
Submitting Laboratory
UVic-Genome BC Proteomics Centre
Submitting Lab PI
Christoph Borchers

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
Agilent 6490/6495 QQQ
Internal Standard
synthetic peptide
Peptide Standard Purity
>80%
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
1290 LC (Agilent)
Column Packing
Zorbax Eclipse Plus C18, 1.8 µm
Column Dimensions
2.1 x 150 mm
Flow Rate
400 µL/min

Chromatograms

Data source: Panorama

view larger image
view larger image
view larger image

Response Curves

Data source: Panorama

view larger image
view larger image
view larger image

Retrieving Data

Loader

Repeatability

Data source: Panorama

view larger image
  Average intra-assay CV
(within day CV)		 Average inter-assay CV
(between day CV)		 Total CV
equation		 n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
b2 (1+) 3.8 2 2.9 8.8 3.6 4.2 9.6 4.1 5.1 15 15 15
y4 (2+) 124.9 111.6 73.3 158 137.8 91.8 201.4 177.3 117.5 15 15 15
y4 (1+) 6.5 3.4 2.7 7.5 5 3 9.9 6 4 15 15 15
y5 (1+) 12 4 2.6 13.7 4.9 5.3 18.2 6.3 5.9 15 15 15
y6 (1+) 2.7 2.4 2.1 6.1 3.2 4.2 6.7 4 4.7 15 15 15
sum 1.9 1.3 1.7 6.1 3.1 3.9 6.4 3.4 4.3 15 15 15

Additional Resources and Comments

Resources
Download SOPs
View Peptide in Panorama
View Protein in Panorama
Comments