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Overview Data source: UniProt

Official Gene Symbol Other Aliases
ROR2 NTRKR2
Sequence Length (AA) Molecular Weight (Da)
943 104757
Protein Name
Tyrosine-protein kinase transmembrane receptor ROR2
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MARGSALPRR PLLCIPAVWA AAALLLSVSR TSGEVEVLDP NDPLGPLDGQ
60 70 80 90 100
DGPIPTLKGY FLNFLEPVNN ITIVQGQTAI LHCKVAGNPP PNVRWLKNDA
110 120 130 140 150
PVVQEPRRII IRKTEYGSRL RIQDLDTTDT GYYQCVATNG MKTITATGVL
160 170 180 190 200
FVRLGPTHSP NHNFQDDYHE DGFCQPYRGI ACARFIGNRT IYVDSLQMQG
210 220 230 240 250
EIENRITAAF TMIGTSTHLS DQCSQFAIPS FCHFVFPLCD ARSRTPKPRE
260 270 280 290 300
LCRDECEVLE SDLCRQEYTI ARSNPLILMR LQLPKCEALP MPESPDAANC
310 320 330 340 350
MRIGIPAERL GRYHQCYNGS GMDYRGTAST TKSGHQCQPW ALQHPHSHHL
360 370 380 390 400
SSTDFPELGG GHAYCRNPGG QMEGPWCFTQ NKNVRMELCD VPSCSPRDSS
410 420 430 440 450
KMGILYILVP SIAIPLVIAC LFFLVCMCRN KQKASASTPQ RRQLMASPSQ
460 470 480 490 500
DMEMPLINQH KQAKLKEISL SAVRFMEELG EDRFGKVYKG HLFGPAPGEQ
510 520 530 540 550
TQAVAIKTLK DKAEGPLREE FRHEAMLRAR LQHPNVVCLL GVVTKDQPLS
560 570 580 590 600
MIFSYCSHGD LHEFLVMRSP HSDVGSTDDD RTVKSALEPP DFVHLVAQIA
610 620 630 640 650
AGMEYLSSHH VVHKDLATRN VLVYDKLNVK ISDLGLFREV YAADYYKLLG
660 670 680 690 700
NSLLPIRWMA PEAIMYGKFS IDSDIWSYGV VLWEVFSYGL QPYCGYSNQD
710 720 730 740 750
VVEMIRNRQV LPCPDDCPAW VYALMIECWN EFPSRRPRFK DIHSRLRAWG
760 770 780 790 800
NLSNYNSSAQ TSGASNTTQT SSLSTSPVSN VSNARYVGPK QKAPPFPQPQ
810 820 830 840 850
FIPMKGQIRP MVPPPQLYVP VNGYQPVPAY GAYLPNFYPV QIPMQMAPQQ
860 870 880 890 900
VPPQMVPKPS SHHSGSGSTS TGYVTTAPSN TSMADRAALL SEGADDTQNA
910 920 930 940 943
PEDGAQSTVQ EAEEEEEGSV PETELLGDCD TLQVDEAQVQ LEA

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-2781 Collapse assay details

Data source: Panorama

Official Gene Symbol
ROR2
Peptide Modified Sequence
NVLVY[+80.0]DK
Modification Type
Phospho (Y)
Protein - Site of Modification
N/A
Peptide - Site of Modification
5
Peptide Start
620
Peptide End
626
CPTAC ID
CPTAC-2781
Peptide Molecular Mass
929.4260
Species
Homo sapiens (Human)
Assay Type
Direct PRM
Matrix
Mammalian Cell Lysate
Submitting Laboratory
Johns Hopkins University / Pandey
Submitting Lab PI
Akhilesh Pandey

Assay Parameters Collapse assay parameters Test button response curves

Data source: Panorama

Instrument
Orbitrap Fusion Lumos
Internal Standard
100fmol
Peptide Standard Purity
Crude (~60%)
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Easy nLC 1200 System
Column Packing
C18 2um 100A
Column Dimensions
75um i.d. x 50cm
Flow Rate
250nl/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y5 (1+) 3.1 3.3 3.6 6.6 3 3.7 7.3 4.5 5.2 15 15 15
y4 (1+) 2.9 3.1 3.1 6.1 2.6 3.8 6.8 4 4.9 15 15 15
y3 (1+) 3.1 2.7 3.4 5.7 2.5 3.8 6.5 3.7 5.1 15 15 15
y2 (1+) 4.2 2.4 2.9 6.6 2.4 3.9 7.8 3.4 4.9 15 15 15
b2 (1+) 3.6 3.1 3.5 6.7 3 3.8 7.6 4.3 5.2 15 15 15
b3 (1+) 6.6 4.1 3 9.5 3.5 5.7 11.6 5.4 6.4 15 15 15
sum 2.9 2.9 3.3 6.2 2.6 3.7 6.8 3.9 5 15 15 15

Additional Resources and Comments