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Please include the following statement when referencing the CPTAC Assay Portal
We would like to acknowledge the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (assays.cancer.gov) for developing assays and establishing criteria for the assays described in this publication.

Overview Data source: UniProt

Official Gene Symbol Other Aliases
Tenm1 Odz1, Tnm1
Sequence Length (AA) Molecular Weight (Da)
2731 305795
Protein Name
Teneurin-1
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MEQTDCKPYQ PLSKVKHEMD LAYTSSSDES EDGRKPRQSF NSRETLHEYN
60 70 80 90 100
QELRRNYNSQ SRKRKDVEKS TQEIEFCETP PTLCSGYHTD MHSVSRHGYQ
110 120 130 140 150
LEMGSDVDTE TEGAASPDHA LRMWIRGMKS EHSSCLSSRA NSALSLTDTD
160 170 180 190 200
HERKSDGENG FKFSPVCCDM EAPADSAQDM QSSPHNQFTF RPLPPPPPPP
210 220 230 240 250
HACTCARKPP PTVDSLQRRS MTTRSQPSPA APAPPTSTQD SVHLHNSWVL
260 270 280 290 300
NSNIPLETRH FLFKHGSGSS AIFSAASQNY PLTSNTVYSP PPRPLPRSTF
310 320 330 340 350
SRPAFTFNKP YRCCNWKCTA LSATAITVTL ALLLAYVIAV HLFGLTWQLQ
360 370 380 390 400
PVGQIYANGI SNGNPGTESM DTTYSPIGGR VSDKSEKKVF QKGRAIDTGE
410 420 430 440 450
VDIGAQVMQT IPPGLFWRFQ ITIHHPIYLK FNISLAKDSL LGIYGRRNIP
460 470 480 490 500
PTHTQFDFVK LMDGKQLVKQ DSKSSDDIQH SPRNLILTSL QETGFIEYMD
510 520 530 540 550
QGPWYLAFYN DGKKMEQVFV LTTAIEIMDD CSTNCNGNGE CISGHCHCFP
560 570 580 590 600
GFLGPDCARD SCPVLCGGNG EYEKGHCVCR NGWKGPECDV PEEQCIDPTC
610 620 630 640 650
FGHGTCIMGV CICVPGYKGE ICEEEDCLDP MCSSHGICVK GECHCSTGWG
660 670 680 690 700
GVNCETPLPI CQEQCSGHGT FLLDTGVCSC DPKWTGSDCS TELCTMECGS
710 720 730 740 750
HGVCSRGICQ CEEGWVGPTC EERSCHSHCA EHGQCKDGKC ECSPGWEGDH
760 770 780 790 800
CTIAHYLDAV RDGCPGLCFG NGRCTLDQNG WHCVCQVGWS GTGCNIVMEM
810 820 830 840 850
LCGDNLDNDG DGLTDCVDPD CCQQSNCYVS PLCQGSPDPL DLIQQSQPLF
860 870 880 890 900
SQHTSRLFYD RIKFLIGKDS THVVPQDISF DSRRACVIRG QVVAVDGTPL
910 920 930 940 950
VGVNVSFLHH SDYGFTISRQ DGSFDLVAIG GISVVLIFDR SPFLSEKRTL
960 970 980 990 1000
WLPWNQFIVV EKVIMQRIVA DAPSCDISNF ISPNPIVLPS PLTSFGGSCP
1010 1020 1030 1040 1050
ERGTIVPELQ VVQEEIPIPS SFVRLSYLSS RTPGYKTLLR ILLTHSTIPV
1060 1070 1080 1090 1100
GMIKVHLTVS VEGRLTQKWF PAAINLVYTF AWNKTDIYGQ KVWGLAEALV
1110 1120 1130 1140 1150
SVGYEYEMCP EFILWEQRTV VLQGFEMDAS NLGGWSLNKH HIFNPQSGII
1160 1170 1180 1190 1200
HKGNGENMFI SQQPPVIATI MGNGHQRSVA CTNCNGPAHN NKLFAPVALA
1210 1220 1230 1240 1250
SGPDGSVYVG DFNFVRRIFP SGNSVSILEL RNRDTRHSTS PAHKYYLAMD
1260 1270 1280 1290 1300
PMSESLYLSD TNTRKVYKLK SLVETKDLSK NFEVVAGTGD QCLPFDQSHC
1310 1320 1330 1340 1350
GDGGKASEAS LNSPRGITVD RHGFIYFVDG TMIRRIDENA VITTVIGSNG
1360 1370 1380 1390 1400
LTSTQPLSCD SGMDITQVRL EWPTDLAVNP MDNSLYVLDN NIVLQISENR
1410 1420 1430 1440 1450
RVRIIAGRPI HCQVPGIDHF LVSKVAIHST LESARAISVS HSGLLFIAET
1460 1470 1480 1490 1500
DERKVNRIQQ VTTNGEISII AGAPTDCDCK IDPNCDCFSG DGGYAKDAKM
1510 1520 1530 1540 1550
KAPSSLAVSP DGTLYVADLG NVRIRTISKN QAHLNDMNLY EIASPADQEL
1560 1570 1580 1590 1600
YQFTVNGTHL HTMNLITRDY VYNFTYNAEG DLGAITSSNG NSVHIRRDAG
1610 1620 1630 1640 1650
GMPLWLVVPG GQVYWLTISS NGVLKRVSAQ GYNLALMTYP GNTGLLATKS
1660 1670 1680 1690 1700
NENGWTTVYE YDPEGHLTNA TFPTGEVSSF HSDLEKLTKV ALDTSNRENV
1710 1720 1730 1740 1750
LMSTNLTATS TIYILKQENT QSTYRVSPDG SLRVTFASGM EINLSSEPHI
1760 1770 1780 1790 1800
LAGAVNPTLG KCNISLPGEH NANLIEWRQR KEQNKGNVSA FERRLRAHNR
1810 1820 1830 1840 1850
NLLSIDFDHM TRTGKIYDDH RKFTLRILYD QTGRPILWSP VSRYNEVNIT
1860 1870 1880 1890 1900
YSPSGLVTFI QRGTWNEKME YDQSGKIISR TWADGKIWSY TYLEKSVMLL
1910 1920 1930 1940 1950
LHSQRRYIFE YDQSDCLLSV TMPSMVRHSL QTMLSVGYYR NIYTPPDSST
1960 1970 1980 1990 2000
SFIQDYSRDG RLLQTLHLGT GRRVLYKYTK QARLSEILYD TTQVTLTYEE
2010 2020 2030 2040 2050
SSGVIKTIHL MHDGFICTIR YRQTGPLIGR QIFRFSEEGL VNARFDYSYN
2060 2070 2080 2090 2100
NFRVTSMQAV INETPLPIDL YRYVDVSGRT EQFGKFSVIN YDLNQVITTT
2110 2120 2130 2140 2150
VMKHTKIFNA NGQVIEVQYE ILKAIAYWMT IQYDNMGRMV ICDIRVGVDA
2160 2170 2180 2190 2200
NITRYFYEYD ADGQLQTVSV NDKIQWRYSY DLNGNINLLS HGNSARLTPL
2210 2220 2230 2240 2250
RYDLRDRITR LGEIQYKMDE DGFLRQRGND IFEYNSNGLL QKAYNKVSGW
2260 2270 2280 2290 2300
TVQYYYDGLG RRVASKSSLG QHLQFFYADL ANPIRVTHLY NHTSAEITSL
2310 2320 2330 2340 2350
YYDLQGHLIA MELSSGEEYY VACDNMGTPL AVFSSRGQVI KEILYTPYGD
2360 2370 2380 2390 2400
IYHDTYPDFE VIIGFHGGLY DFLTKLVHLG QRDYDVVAGR WTTPNHHIWK
2410 2420 2430 2440 2450
QLNLLPKPFN LYSFENNYPV GKIQDVAKYT TDIGTWLELF GFQLHNVLPG
2460 2470 2480 2490 2500
FPKPELENME LTYELLQLQT KTQEWDPGKM ILGIQCELQK QLRNFISLDQ
2510 2520 2530 2540 2550
LPMTPQYNEG RCLEGGKQPR FAAVPSVFGK GIKFAIKEGI VTADIIGVAN
2560 2570 2580 2590 2600
EDSRRLAAIL NNAHYLENLH FTIEGRDTHY FIKLGSLEED LVLIGNTGGR
2610 2620 2630 2640 2650
RILENGVNVT VSQMTSVLNG RTRRFADIQL QHGALCFNIR YGTTVEEEKN
2660 2670 2680 2690 2700
HVLEMARQRA VAQAWTQEQR RLQEGEEGTR VWTEGEKQQL LGTGRVQGYD
2710 2720 2730 2731
GYFVLSVEQY LELSDSANNI HFMRQSEIGR R

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

Click a point on a node
to view detailed assay information below
All other points link out to UniProt



Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for non-CPTAC-4065 Collapse assay details

Data source: Panorama

Official Gene Symbol
Tenm1
Peptide Sequence
YGTTVEEEK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
2641
Peptide End
2649
CPTAC ID
non-CPTAC-4065
Peptide Molecular Mass
1,054.4819
Species
Mus musculus (Mouse)
Assay Type
Direct MRM
Matrix
Plasma
Submitting Laboratory
UVic-Genome BC Proteomics Centre
Submitting Lab PI
Christoph Borchers

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
Agilent 6490/6495 QQQ
Internal Standard
synthetic peptide
Peptide Standard Purity
>80%
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
1290 LC (Agilent)
Column Packing
Zorbax Eclipse Plus C18, 1.8 µm
Column Dimensions
2.1 x 150 mm
Flow Rate
400 µL/min

Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

Loader

Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
b2 (1+) 9.7 6.4 5.9 11 8.4 7.2 14.7 10.6 9.3 15 15 15
y3 (1+) 19.7 11.4 9.8 18.6 15.1 10.9 27.1 18.9 14.7 15 15 15
y4 (1+) 13.3 4.6 7.9 16 7.6 6.3 20.8 8.9 10.1 15 15 15
y6 (1+) 7.9 9 4.5 11.1 11.8 5.9 13.6 14.8 7.4 15 15 15
y8 (1+) 14.6 5.6 6.9 16.2 11.3 6.9 21.8 12.6 9.8 15 15 15
sum 5.4 2.1 2.9 6.7 6.5 3.9 8.6 6.8 4.9 15 15 15


Additional Resources and Comments