| Official Gene Symbol | Other Aliases |
|---|---|
| ERBB2 | HER2, MLN19, NEU, NGL |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 1255 | 137910 |
| Protein Name |
|---|
| Receptor tyrosine-protein kinase erbB-2 |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MELAALCRWG | LLLALLPPGA | ASTQVCTGTD | MKLRLPASPE | THLDMLRHLY |
| 60 | 70 | 80 | 90 | 100 |
| QGCQVVQGNL | ELTYLPTNAS | LSFLQDIQEV | QGYVLIAHNQ | VRQVPLQRLR |
| 110 | 120 | 130 | 140 | 150 |
| IVRGTQLFED | NYALAVLDNG | DPLNNTTPVT | GASPGGLREL | QLRSLTEILK |
| 160 | 170 | 180 | 190 | 200 |
| GGVLIQRNPQ | LCYQDTILWK | DIFHKNNQLA | LTLIDTNRSR | ACHPCSPMCK |
| 210 | 220 | 230 | 240 | 250 |
| GSRCWGESSE | DCQSLTRTVC | AGGCARCKGP | LPTDCCHEQC | AAGCTGPKHS |
| 260 | 270 | 280 | 290 | 300 |
| DCLACLHFNH | SGICELHCPA | LVTYNTDTFE | SMPNPEGRYT | FGASCVTACP |
| 310 | 320 | 330 | 340 | 350 |
| YNYLSTDVGS | CTLVCPLHNQ | EVTAEDGTQR | CEKCSKPCAR | VCYGLGMEHL |
| 360 | 370 | 380 | 390 | 400 |
| REVRAVTSAN | IQEFAGCKKI | FGSLAFLPES | FDGDPASNTA | PLQPEQLQVF |
| 410 | 420 | 430 | 440 | 450 |
| ETLEEITGYL | YISAWPDSLP | DLSVFQNLQV | IRGRILHNGA | YSLTLQGLGI |
| 460 | 470 | 480 | 490 | 500 |
| SWLGLRSLRE | LGSGLALIHH | NTHLCFVHTV | PWDQLFRNPH | QALLHTANRP |
| 510 | 520 | 530 | 540 | 550 |
| EDECVGEGLA | CHQLCARGHC | WGPGPTQCVN | CSQFLRGQEC | VEECRVLQGL |
| 560 | 570 | 580 | 590 | 600 |
| PREYVNARHC | LPCHPECQPQ | NGSVTCFGPE | ADQCVACAHY | KDPPFCVARC |
| 610 | 620 | 630 | 640 | 650 |
| PSGVKPDLSY | MPIWKFPDEE | GACQPCPINC | THSCVDLDDK | GCPAEQRASP |
| 660 | 670 | 680 | 690 | 700 |
| LTSIISAVVG | ILLVVVLGVV | FGILIKRRQQ | KIRKYTMRRL | LQETELVEPL |
| 710 | 720 | 730 | 740 | 750 |
| TPSGAMPNQA | QMRILKETEL | RKVKVLGSGA | FGTVYKGIWI | PDGENVKIPV |
| 760 | 770 | 780 | 790 | 800 |
| AIKVLRENTS | PKANKEILDE | AYVMAGVGSP | YVSRLLGICL | TSTVQLVTQL |
| 810 | 820 | 830 | 840 | 850 |
| MPYGCLLDHV | RENRGRLGSQ | DLLNWCMQIA | KGMSYLEDVR | LVHRDLAARN |
| 860 | 870 | 880 | 890 | 900 |
| VLVKSPNHVK | ITDFGLARLL | DIDETEYHAD | GGKVPIKWMA | LESILRRRFT |
| 910 | 920 | 930 | 940 | 950 |
| HQSDVWSYGV | TVWELMTFGA | KPYDGIPARE | IPDLLEKGER | LPQPPICTID |
| 960 | 970 | 980 | 990 | 1000 |
| VYMIMVKCWM | IDSECRPRFR | ELVSEFSRMA | RDPQRFVVIQ | NEDLGPASPL |
| 1010 | 1020 | 1030 | 1040 | 1050 |
| DSTFYRSLLE | DDDMGDLVDA | EEYLVPQQGF | FCPDPAPGAG | GMVHHRHRSS |
| 1060 | 1070 | 1080 | 1090 | 1100 |
| STRSGGGDLT | LGLEPSEEEA | PRSPLAPSEG | AGSDVFDGDL | GMGAAKGLQS |
| 1110 | 1120 | 1130 | 1140 | 1150 |
| LPTHDPSPLQ | RYSEDPTVPL | PSETDGYVAP | LTCSPQPEYV | NQPDVRPQPP |
| 1160 | 1170 | 1180 | 1190 | 1200 |
| SPREGPLPAA | RPAGATLERP | KTLSPGKNGV | VKDVFAFGGA | VENPEYLTPQ |
| 1210 | 1220 | 1230 | 1240 | 1250 |
| GGAAPQPHPP | PAFSPAFDNL | YYWDQDPPER | GAPPSTFKGT | PTAENPEYLG |
| 1255 | ||||
| LDVPV |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins. Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8. PMID: 24317253
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y6 (1+) | 7.8 | 6.6 | 6.8 | 9.4 | 15 | 12.8 | 12.2 | 16.4 | 14.5 | 15 | 25 | 15 |
| y5 (1+) | 10.9 | 5 | 5.7 | 15.3 | 10.8 | 11.2 | 18.8 | 11.9 | 12.6 | 15 | 25 | 15 |
| y4 (1+) | 9.7 | 5.1 | 8 | 13.6 | 10.5 | 13.5 | 16.7 | 11.7 | 15.7 | 15 | 25 | 15 |
| sum | 8.5 | 5.2 | 6.2 | 12.9 | 11.7 | 11.8 | 15.4 | 12.8 | 13.3 | 15 | 25 | 15 |
Data source: Panorama
View Details (opens in a new window)
Quantification of Human Epidermal Growth Factor Receptor 2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded and Frozen Breast Cancer Tissues. Kennedy JJ, Whiteaker JR, Kennedy LC, Bosch DE, Lerch ML, Schoenherr RM, Zhao L, Lin C, Chowdhury S, Kilgore MR, Allison KH, Wang P, Hoofnagle AN, Baird GS, Paulovich AG. Clin Chem. 2021 Jun 17:hvab047. doi: 10.1093/clinchem/hvab047. Online ahead of print. PMID: 34136904
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y12 (2+) | 16.2 | 5.2 | 3.9 | 17.2 | 9.3 | 4.3 | 23.6 | 10.7 | 5.8 | 12 | 12 | 12 |
| y13 (2+) | 22.2 | 9.7 | 3.8 | 16.8 | 12.8 | 3.6 | 27.8 | 16.1 | 5.2 | 12 | 12 | 12 |
| y6 (1+) | 17.3 | 5.9 | 3.6 | 13.4 | 6.2 | 3.6 | 21.9 | 8.6 | 5.1 | 12 | 12 | 12 |
| y10 (2+) | 16 | 3.8 | 5.5 | 13.2 | 5.9 | 4.3 | 20.7 | 7 | 7 | 12 | 12 | 12 |
| sum | 16.7 | 4.2 | 3.6 | 13.5 | 7 | 3 | 21.5 | 8.2 | 4.7 | 12 | 12 | 12 |
Data source: Panorama
View Details (opens in a new window)
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins. Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8. PMID: 24317253
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y13 (2+) | 8 | 4.2 | 3.6 | 8.8 | 6.9 | 4.8 | 11.9 | 8.1 | 6 | 15 | 25 | 15 |
| y12 (2+) | 3.3 | 4.4 | 3.7 | 6.9 | 5.9 | 4.3 | 7.6 | 7.4 | 5.7 | 15 | 25 | 15 |
| y10 (2+) | 3.7 | 5.3 | 3.2 | 6.7 | 6.1 | 4.4 | 7.7 | 8.1 | 5.4 | 15 | 25 | 15 |
| sum | 3.5 | 4.2 | 3.1 | 6.8 | 5.8 | 4.2 | 7.6 | 7.2 | 5.2 | 15 | 25 | 15 |
Data source: Panorama
View Details (opens in a new window)
Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA. Schoenherr RM, Saul RG, Whiteaker JR, Yan P, Whiteley GR, Paulovich AG. Mol Cell Proteomics. 2015 Feb;14(2):382-98. doi: 10.1074/mcp.O114.043133. Epub 2014 Dec 15. PMID: 25512614
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y10 (2+) | 15.4 | 3.5 | 1.9 | 21.9 | 4.1 | 4.4 | 26.8 | 5.4 | 4.8 | 15 | 15 | 15 |
| y4 (1+) | 22.6 | 5.5 | 2.4 | 26.3 | 6.8 | 4.9 | 34.7 | 8.7 | 5.5 | 15 | 15 | 15 |
| y6 (1+) | 16.8 | 4.9 | 2.8 | 18 | 6.9 | 5 | 24.6 | 8.5 | 5.7 | 15 | 15 | 15 |
| sum | 13.6 | 2.8 | 1.4 | 18.5 | 4.2 | 4.3 | 23 | 5 | 4.5 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Quantification of Human Epidermal Growth Factor Receptor 2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded and Frozen Breast Cancer Tissues. Kennedy JJ, Whiteaker JR, Kennedy LC, Bosch DE, Lerch ML, Schoenherr RM, Zhao L, Lin C, Chowdhury S, Kilgore MR, Allison KH, Wang P, Hoofnagle AN, Baird GS, Paulovich AG. Clin Chem. 2021 Jun 17:hvab047. doi: 10.1093/clinchem/hvab047. Online ahead of print. PMID: 34136904
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y6 (1+) | 14.6 | 4.6 | 3.3 | 15 | 4.9 | 4.1 | 20.9 | 6.7 | 5.3 | 15 | 17 | 15 |
| y13 (2+) | 12.8 | 6.8 | 3.5 | 16.9 | 8.1 | 5.3 | 21.2 | 10.6 | 6.4 | 15 | 17 | 15 |
| y12 (2+) | 11.1 | 3.8 | 3.7 | 8.9 | 5.1 | 4.1 | 14.2 | 6.4 | 5.5 | 15 | 17 | 15 |
| y10 (2+) | 17.4 | 4.4 | 3.7 | 16.6 | 4.9 | 4.8 | 24 | 6.6 | 6.1 | 15 | 17 | 15 |
| sum | 11.5 | 3.3 | 2.7 | 11.5 | 4.6 | 4.1 | 16.3 | 5.7 | 4.9 | 15 | 17 | 15 |
Data source: Panorama
View Details (opens in a new window)
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins. Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8. PMID: 24317253
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 29.9 | 22.1 | 10.9 | 21.6 | 28.9 | 18.4 | 36.9 | 36.4 | 21.4 | 15 | 25 | 15 |
| y13 (2+) | 8.5 | 6.1 | 7.3 | 21.4 | 18.2 | 22.9 | 23 | 19.2 | 24 | 15 | 25 | 15 |
| y12 (2+) | 20.7 | 15.2 | 15.4 | 23.7 | 23.5 | 25.6 | 31.5 | 28 | 29.9 | 15 | 25 | 15 |
| sum | 8.3 | 6.8 | 7.9 | 20.4 | 18 | 22.3 | 22 | 19.2 | 23.7 | 15 | 25 | 15 |
Data source: Panorama
View Details (opens in a new window)
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins. Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8. PMID: 24317253
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 15.2 | 9.4 | 10.7 | 15.3 | 10.7 | 15.6 | 21.6 | 14.2 | 18.9 | 25 | 15 | 15 |
| y8 (1+) | 15.5 | 8.7 | 5.7 | 17.3 | 7.1 | 9.2 | 23.2 | 11.2 | 10.8 | 25 | 15 | 15 |
| y9 (1+) | 11.6 | 8 | 4.4 | 12.4 | 7.2 | 11 | 17 | 10.8 | 11.8 | 25 | 15 | 15 |
| sum | 9.3 | 7.3 | 5.4 | 10.1 | 5.9 | 9.9 | 13.7 | 9.4 | 11.3 | 25 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b3 (1+) | 40.7 | 12 | 14.8 | 39.2 | 26.6 | 19 | 56.5 | 29.2 | 24.1 | 15 | 15 | 15 |
| y7 (1+) | 29.1 | 10.5 | 13.7 | 23.9 | 28.1 | 19.3 | 37.7 | 30 | 23.7 | 15 | 15 | 15 |
| y5 (1+) | 57 | 15.1 | 16.4 | 74 | 30.1 | 18.7 | 93.4 | 33.7 | 24.9 | 15 | 15 | 15 |
| sum | 38.2 | 9.8 | 14.1 | 34.4 | 27.4 | 19.1 | 51.4 | 29.1 | 23.7 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b10 (1+) | 17.2 | 13.7 | 6.1 | 21.1 | 15.7 | 6.7 | 27.2 | 20.8 | 9.1 | 16 | 15 | 13 |
| b7 (1+) | 16.8 | 13.7 | 9.3 | 20.2 | 15.5 | 7.1 | 26.3 | 20.7 | 11.7 | 16 | 15 | 13 |
| sum | 16.4 | 13.4 | 7.6 | 18.1 | 15.5 | 6.8 | 24.4 | 20.5 | 10.2 | 16 | 15 | 13 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y3 (1+) | 3.9 | 1.6 | 3.5 | 4.5 | 2.9 | 3.2 | 6 | 3.3 | 4.7 | 15 | 15 | 15 |
| y4 (1+) | 9.2 | 3 | 3 | 8.7 | 5.7 | 3.6 | 12.7 | 6.4 | 4.7 | 15 | 15 | 15 |
| y5 (1+) | 3.1 | 1.8 | 2.8 | 3 | 3.1 | 2.7 | 4.3 | 3.6 | 3.9 | 15 | 15 | 15 |
| y6 (1+) | 7.2 | 3.7 | 2.4 | 7.5 | 3.8 | 3 | 10.4 | 5.3 | 3.8 | 15 | 15 | 15 |
| sum | 2.9 | 1.5 | 2.1 | 3 | 3 | 2.2 | 4.2 | 3.4 | 3 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b3 (1+) | 44.7 | 13 | 12.1 | 39.2 | 32.4 | 19.4 | 59.5 | 34.9 | 22.9 | 11 | 11 | 11 |
| y5 (1+) | 57 | 13.3 | 14.4 | 67.7 | 37.5 | 20.2 | 88.5 | 39.8 | 24.8 | 11 | 11 | 11 |
| y7 (1+) | 32.8 | 12.5 | 11.4 | 23.3 | 34.4 | 19.2 | 40.2 | 36.6 | 22.3 | 11 | 11 | 11 |
| y8 (1+) | 41.1 | 13.8 | 10.3 | 37.1 | 33.2 | 17.1 | 55.4 | 36 | 20 | 11 | 11 | 11 |
| y9 (1+) | 40.5 | 15.6 | 12.7 | 35.8 | 35.5 | 18.7 | 54.1 | 38.8 | 22.6 | 11 | 11 | 11 |
| sum | 42.8 | 11.1 | 11.7 | 34.7 | 33.8 | 19.1 | 55.1 | 35.6 | 22.4 | 11 | 11 | 11 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b14 (1+) | 45.2 | 14.4 | 70.4 | 45.3 | 16.4 | 76.4 | 64 | 21.8 | 103.9 | 15 | 15 | 15 |
| b7 (1+) | 38.5 | 14.8 | 11 | 39.1 | 15 | 11.4 | 54.9 | 21.1 | 15.8 | 15 | 15 | 15 |
| b6 (1+) | 23.9 | 18.5 | 7 | 29.3 | 22 | 4.9 | 37.8 | 28.7 | 8.5 | 15 | 15 | 15 |
| sum | 15.9 | 13.8 | 9.9 | 17.5 | 13.2 | 9.8 | 23.6 | 19.1 | 13.9 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b7 (1+) | 6.9 | 5.8 | 2.7 | 8.2 | 5.7 | 2.7 | 10.7 | 8.1 | 3.8 | 15 | 15 | 15 |
| b6 (1+) | 4.8 | 4.2 | 2.8 | 5.6 | 4.7 | 3 | 7.4 | 6.3 | 4.1 | 15 | 15 | 15 |
| y3 (1+) | 3.9 | 2.4 | 1.7 | 3.4 | 3.8 | 3.2 | 5.2 | 4.5 | 3.6 | 15 | 15 | 15 |
| sum | 3.1 | 1.8 | 1.3 | 2.6 | 2.3 | 1.7 | 4 | 2.9 | 2.1 | 15 | 15 | 15 |
| b11 (1+) | 5.8 | 4.9 | 2.4 | 5.8 | 3.9 | 3.6 | 8.2 | 6.3 | 4.3 | 15 | 15 | 15 |
| b10 (1+) | 6.3 | 5.3 | 3 | 6.1 | 5.2 | 3.5 | 8.8 | 7.4 | 4.6 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 11.1 | 6.2 | 2 | 11.3 | 7.5 | 3 | 15.8 | 9.7 | 3.6 | 15 | 15 | 15 |
| y8 (1+) | 17.6 | 6.4 | 3.3 | 18.9 | 8.2 | 3.5 | 25.8 | 10.4 | 4.8 | 15 | 15 | 15 |
| y9 (1+) | 7.5 | 5.1 | 7.1 | 8.2 | 6 | 7.9 | 11.1 | 7.9 | 10.6 | 15 | 15 | 15 |
| y5 (1+) | 10.6 | 5.2 | 4.7 | 12.8 | 4.1 | 4.1 | 16.6 | 6.6 | 6.2 | 15 | 15 | 15 |
| y6 (1+) | 17.4 | 5.1 | 4 | 15 | 4.4 | 4.1 | 23 | 6.7 | 5.7 | 15 | 15 | 15 |
| sum | 6.2 | 4.6 | 3 | 7.1 | 4.1 | 3.2 | 9.4 | 6.2 | 4.4 | 15 | 15 | 15 |
Data source: Panorama
View Details (opens in a new window)
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Whiteaker JR, Sharma K, Hoffman MA, Kuhn E, Zhao L, Cocco AR, Schoenherr RM, Kennedy JJ, Voytovich U, Lin C, Fang B, Bowers K, Whiteley G, Colantonio S, Bocik W, Roberts R, Hiltke T, Boja E, Rodriguez H, McCormick F, Holderfield M, Carr SA, Koomen JM, Paulovich AG. Cell Reports Methods doi: 10.1016/j.crmeth.2021.100015.
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y11 (2+) | 2.8 | 3.5 | 2.7 | 4.7 | 3.9 | 3.9 | 5.5 | 5.2 | 4.7 | 15 | 15 | 15 |
| y13 (2+) | 10.9 | 2.6 | 1.8 | 17 | 5 | 2.2 | 20.2 | 5.6 | 2.8 | 15 | 15 | 15 |
| y7 (1+) | 8.5 | 5.5 | 3.9 | 10 | 6 | 5.7 | 13.1 | 8.1 | 6.9 | 15 | 15 | 15 |
| y9 (1+) | 6.9 | 3.3 | 3 | 6.1 | 5.9 | 4 | 9.2 | 6.8 | 5 | 15 | 15 | 15 |
| sum | 9.3 | 2.3 | 1.3 | 14.3 | 4.4 | 2.2 | 17.1 | 5 | 2.6 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y3 (1+) | 44.1 | 4.3 | 9.8 | 62.8 | 6.2 | 10.4 | 76.7 | 7.5 | 14.3 | 15 | 15 | 15 |
| y11 (1+) | 13.8 | 7.2 | 8.7 | 12.4 | 6.8 | 8.7 | 18.6 | 9.9 | 12.3 | 15 | 15 | 15 |
| y6 (1+) | 12.1 | 6.4 | 8.7 | 17.6 | 6.8 | 8.1 | 21.4 | 9.3 | 11.9 | 15 | 15 | 15 |
| sum | 12.2 | 5.8 | 8.7 | 21.5 | 6.1 | 8.7 | 24.7 | 8.4 | 12.3 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y9 (1+) | 9.4 | 6.9 | 9.1 | 16.9 | 9.5 | 12.6 | 19.3 | 11.7 | 15.5 | 15 | 15 | 15 |
| b3 (1+) | 11 | 4.7 | 7.3 | 15.8 | 7 | 10.2 | 19.3 | 8.4 | 12.5 | 15 | 15 | 15 |
| y7 (1+) | 8.8 | 4.7 | 8.1 | 15.2 | 6.4 | 11.2 | 17.6 | 7.9 | 13.8 | 15 | 15 | 15 |
| sum | 9.2 | 5.4 | 8.1 | 15.9 | 7.6 | 11.3 | 18.4 | 9.3 | 13.9 | 15 | 15 | 15 |
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