| Official Gene Symbol | Other Aliases |
|---|---|
| AURKB | AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 344 | 39311 |
| Protein Name |
|---|
| Aurora kinase B |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MAQKENSYPW | PYGRQTAPSG | LSTLPQRVLR | KEPVTPSALV | LMSRSNVQPT |
| 60 | 70 | 80 | 90 | 100 |
| AAPGQKVMEN | SSGTPDILTR | HFTIDDFEIG | RPLGKGKFGN | VYLAREKKSH |
| 110 | 120 | 130 | 140 | 150 |
| FIVALKVLFK | SQIEKEGVEH | QLRREIEIQA | HLHHPNILRL | YNYFYDRRRI |
| 160 | 170 | 180 | 190 | 200 |
| YLILEYAPRG | ELYKELQKSC | TFDEQRTATI | MEELADALMY | CHGKKVIHRD |
| 210 | 220 | 230 | 240 | 250 |
| IKPENLLLGL | KGELKIADFG | WSVHAPSLRR | KTMCGTLDYL | PPEMIEGRMH |
| 260 | 270 | 280 | 290 | 300 |
| NEKVDLWCIG | VLCYELLVGN | PPFESASHNE | TYRRIVKVDL | KFPASVPMGA |
| 310 | 320 | 330 | 340 | 344 |
| QDLISKLLRH | NPSERLPLAQ | VSAHPWVRAN | SRRVLPPSAL | QSVA |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
View Details (opens in a new window)
Abelin, et al. Mol Cell Proteomics. 2016 May;15(5):1622-41. doi: 10.1074/mcp.M116.058354. Epub 2016 Feb 24. PMID:26912667
Data source: Panorama
Broad Institute-Biologist curated set of targets across a number of important cancer pathways
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y8 (1+) | 17.6 | 6.6 | 4.9 | 17.5 | 8 | 8.4 | 24.8 | 10.4 | 9.7 | 15 | 15 | 15 |
| y7 (1+) | 29.4 | 9.4 | 11.9 | 28.3 | 14.7 | 15.8 | 40.8 | 17.4 | 19.8 | 15 | 15 | 15 |
| y8 (2+) | 4.3 | 5.2 | 3.9 | 5 | 6.2 | 9.7 | 6.6 | 8.1 | 10.5 | 15 | 15 | 15 |
| sum | 6.2 | 4.3 | 3.2 | 7.8 | 5.5 | 8.9 | 10 | 7 | 9.5 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Broad Institute-Biologist curated set of targets across a number of important cancer pathways
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y4 (1+) | 31.7 | 7.6 | 7 | 32.2 | 12.3 | 18.9 | 45.2 | 14.5 | 20.2 | 15 | 15 | 15 |
| y7 (1+) | 41.4 | 9.1 | 8 | 51.2 | 20.4 | 15.7 | 65.8 | 22.3 | 17.6 | 15 | 15 | 15 |
| y8 (1+) | 65 | 21.9 | 10.3 | 68.8 | 23.6 | 15.8 | 94.6 | 32.2 | 18.9 | 15 | 15 | 15 |
| sum | 27.3 | 7.2 | 4.9 | 31.1 | 14.8 | 16.3 | 41.4 | 16.5 | 17 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Broad Institute-Biologist curated set of targets across a number of important cancer pathways
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y4 (1+) | 34.7 | 11.7 | 17.9 | 49.5 | 14.5 | 18.4 | 60.5 | 18.6 | 25.7 | 15 | 15 | 15 |
| y5 (1+) | 67.3 | 15.6 | 19.7 | 78.2 | 16.1 | 20.6 | 103.2 | 22.4 | 28.5 | 15 | 15 | 15 |
| y8 (1+) | 29.3 | 17.9 | 15.5 | 36.5 | 23.8 | 18 | 46.8 | 29.8 | 23.8 | 15 | 15 | 15 |
| sum | 25.8 | 14.1 | 14.4 | 28.9 | 19.8 | 16.5 | 38.7 | 24.3 | 21.9 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Broad Institute-Biologist curated set of targets across a number of important cancer pathways
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y6 (1+) | 7.9 | 4.4 | 6.4 | 8.3 | 6.6 | 10.5 | 11.5 | 7.9 | 12.3 | 15 | 15 | 15 |
| y7 (1+) | 8.1 | 4.7 | 6.5 | 8.6 | 6.2 | 10.1 | 11.8 | 7.8 | 12 | 15 | 15 | 15 |
| b6 (1+) | 5.4 | 4.6 | 7.1 | 7 | 5.8 | 10 | 8.8 | 7.4 | 12.3 | 15 | 15 | 15 |
| sum | 6.9 | 4.5 | 6.6 | 7.7 | 6 | 10.2 | 10.3 | 7.5 | 12.1 | 15 | 15 | 15 |
Data source: Panorama
Data source: Panorama
Broad Institute-Biologist curated set of targets across a number of important cancer pathways
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y4 (1+) | 4.1 | 3.9 | 3.7 | 6.2 | 3.7 | 5.3 | 7.4 | 5.4 | 6.5 | 15 | 15 | 15 |
| y8 (1+) | 3.5 | 4.2 | 4.4 | 7.1 | 4.7 | 6.6 | 7.9 | 6.3 | 7.9 | 15 | 15 | 15 |
| y7 (1+) | 4.1 | 4.4 | 4.5 | 7.9 | 4.4 | 6.5 | 8.9 | 6.2 | 7.9 | 15 | 15 | 15 |
| sum | 3.6 | 4 | 3.9 | 6.6 | 3.7 | 5.6 | 7.5 | 5.4 | 6.8 | 15 | 15 | 15 |
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