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Overview Data source: UniProt

Official Gene Symbol Other Aliases
KRT7 SCL
Sequence Length (AA) Molecular Weight (Da)
469 51386
Protein Name
Keratin, type II cytoskeletal 7
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MSIHFSSPVF TSRSAAFSGR GAQVRLSSAR PGGLGSSSLY GLGASRPRVA
60 70 80 90 100
VRSAYGGPVG AGIREVTINQ SLLAPLRLDA DPSLQRVRQE ESEQIKTLNN
110 120 130 140 150
KFASFIDKVR FLEQQNKLLE TKWTLLQEQK SAKSSRLPDI FEAQIAGLRG
160 170 180 190 200
QLEALQVDGG RLEAELRSMQ DVVEDFKNKY EDEINHRTAA ENEFVVLKKD
210 220 230 240 250
VDAAYMSKVE LEAKVDALND EINFLRTLNE TELTELQSQI SDTSVVLSMD
260 270 280 290 300
NSRSLDLDGI IAEVKAQYEE MAKCSRAEAE AWYQTKFETL QAQAGKHGDD
310 320 330 340 350
LRNTRNEISE MNRAIQRLQA EIDNIKNQRA KLEAAIAEAE ERGELALKDA
360 370 380 390 400
RAKQEELEAA LQRGKQDMAR QLREYQELMS VKLALDIEIA TYRKLLEGEE
410 420 430 440 450
SRLAGDGVGA VNISVMNSTG GSSSGGGIGL TLGGTMGSNA LSFSSSAGPG
460 469
LLKAYSIRTA SASRRSARD

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-1520 Collapse assay details

Data source: Panorama

Official Gene Symbol
KRT7
Peptide Sequence
SAYGGPVGAGIR
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
53
Peptide End
64
CPTAC ID
CPTAC-1520
Peptide Molecular Mass
1,103.5724
Species
Homo sapiens (Human)
Assay Type
Direct MRM or SRM
Matrix
Ovarian cancer tumor tissue lysate
Submitting Laboratory
Pacific Northwest National Laboratory
Submitting Lab PI
Tao Liu

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
Waters nanoACQUITY (Part Number 176016000)
Column Packing
Waters BEH C18, 1.7 um 130 Å (Part Number 186007485)
Column Dimensions
100 um x 100 mm
Flow Rate
0.4 uL/min

Assay Multiplexing Expand assay panel

Pacific Northwest National Laboratory-DirectSRM1


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y10 (2+) 5.8 8 3 40.3 29.3 29.2 40.7 30.4 29.4 15 15 15
y7 (1+) 6.1 7.7 2.2 25.7 27.7 28.3 26.4 28.8 28.4 15 15 15
y9 (1+) 4.7 5.4 0.9 38 29.1 29.6 38.3 29.6 29.6 15 15 15
sum 3 6.6 1.4 35.4 28.8 29.1 35.5 29.5 29.1 15 15 15

Additional Resources and Comments


Assay Details for CPTAC-1521 Collapse assay details

Data source: Panorama

Official Gene Symbol
KRT7
Peptide Sequence
SLDLDGIIAEVK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
N/A
Peptide Start
254
Peptide End
265
CPTAC ID
CPTAC-1521
Peptide Molecular Mass
1,271.6973
Species
Homo sapiens (Human)
Assay Type
Direct MRM or SRM
Matrix
Ovarian cancer tumor tissue lysate
Submitting Laboratory
Pacific Northwest National Laboratory
Submitting Lab PI
Tao Liu

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Waters nanoACQUITY (Part Number 176016000)
Column Packing
Waters BEH C18, 1.7 um 130 Å (Part Number 186007485)
Column Dimensions
100 um x 100 mm
Flow Rate
0.4 uL/min

Assay Multiplexing Expand assay panel

Pacific Northwest National Laboratory-DirectSRM1


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

Loader

Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y7 (1+) 8.6 5.9 1.6 51 39.2 43.1 51.7 39.6 43.1 15 15 15
y8 (1+) 5.6 5.2 2.8 47.9 40.9 44.6 48.2 41.2 44.7 15 15 15
y10 (1+) 4.6 5.3 3.1 52.2 41.5 44.6 52.4 41.8 44.7 15 15 15
sum 3.7 5.1 2 50.2 40.7 44.2 50.3 41 44.2 15 15 15

Additional Resources and Comments