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Overview Data source: UniProt

Official Gene Symbol Other Aliases
CABLES1 CABLES
Sequence Length (AA) Molecular Weight (Da)
633 67599
Protein Name
CDK5 and ABL1 enzyme substrate 1
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MAAAAAAATT AACSSGSAGT DAAGASGLQQ PPPQPQPQPA AAAPAQPPPE
60 70 80 90 100
PPRKPRMDPR RRQAALSFLT NISLDGRLPP QDAEWGGGEE GGAAKPGAGG
110 120 130 140 150
ACGARTRFSL LAAAERGGCI ALAAPGTPAA GLAAGSGPCL PQPSSLPPLI
160 170 180 190 200
PGGHATVSGP GVARGFASPL GAGRASGEQW QPPRPAPLAA CAQLQLLDGS
210 220 230 240 250
GAAGQEELEE DDAFISVQVP AAAFLGSGTP GSGSGSRGRL NSFTQGILPI
260 270 280 290 300
AFSRPTSQNY CSLEQPGQGG STSAFEQLQR SRRRLISQRS SLETLEDIEE
310 320 330 340 350
NAPLRRCRTL SGSPRPKNFK KIHFIKNMRQ HDTRNGRIVL ISGRRSFCSI
360 370 380 390 400
FSVLPYRDST QVGDLKLDGG RQSTGAVSLK EIIGLEGVEL GADGKTVSYT
410 420 430 440 450
QFLLPTNAFG ARRNTIDSTS SFSQFRNLSH RSLSIGRASG TQGSLDTGSD
460 470 480 490 500
LGDFMDYDPN LLDDPQWPCG KHKRVLIFPS YMTTVIDYVK PSDLKKDMNE
510 520 530 540 550
TFKEKFPHIK LTLSKIRSLK REMRKLAQED CGLEEPTVAM AFVYFEKLAL
560 570 580 590 600
KGKLNKQNRK LCAGACVLLA AKIGSDLKKH EVKHLIDKLE EKFRLNRREL
610 620 630 633
IAFEFPVLVA LEFALHLPEH EVMPHYRRLV QSS

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-1742 Collapse assay details

Data source: Panorama

Official Gene Symbol
CABLES1
Peptide Modified Sequence
NTIDSTSS[+80.0]FSQFR
Modification Type
Phospho (ST)
Protein - Site of Modification
421
Peptide - Site of Modification
8
Peptide Start
414
Peptide End
426
CPTAC ID
CPTAC-1742
Peptide Molecular Mass
1,568.6508
Species
Homo sapiens (Human)
Assay Type
Enrichment MRM or SRM
Enrichment Method
Titanium Dioxide
Matrix
Ovarian cancer cell lysate
Submitting Laboratory
Pacific Northwest National Laboratory
Submitting Lab PI
Tao Liu

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
Waters nanoACQUITY (Part Number 176016000)
Column Packing
Waters BEH C18, 1.7 um 130 Å (Part Number 186007485)
Column Dimensions
100 um x 100 mm
Flow Rate
0.5 uL/min

Assay Multiplexing Expand assay panel

Pacific Northwest National Laboratory-TiO2SRM


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y2 (1+) 7 4.5 4.8 12.3 4.6 10 14.2 6.4 11.1 15 15 15
y4 (1+) 18.5 5.5 5.3 19.1 7 6.2 26.6 8.9 8.2 15 15 15
y9 (1+) 28.9 14.5 4.8 31 18.4 11 42.4 23.4 12 15 15 15
sum 11.1 3 3.9 11.1 4.6 6.6 15.7 5.5 7.7 15 15 15


Additional Resources and Comments


Assay Details for CPTAC-1741 Collapse assay details

Data source: Panorama

Official Gene Symbol
CABLES1
Peptide Modified Sequence
QS[+80.0]TGAVSLK
Modification Type
Phospho (ST)
Protein - Site of Modification
373
Peptide - Site of Modification
2
Peptide Start
372
Peptide End
380
CPTAC ID
CPTAC-1741
Peptide Molecular Mass
969.4532
Species
Homo sapiens (Human)
Assay Type
Enrichment MRM or SRM
Enrichment Method
Titanium Dioxide
Matrix
Ovarian cancer cell lysate
Submitting Laboratory
Pacific Northwest National Laboratory
Submitting Lab PI
Tao Liu

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
peptide
Peptide Standard Purity
>95%
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Waters nanoACQUITY (Part Number 176016000)
Column Packing
Waters BEH C18, 1.7 um 130 Å (Part Number 186007485)
Column Dimensions
100 um x 100 mm
Flow Rate
0.5 uL/min

Assay Multiplexing Expand assay panel

Pacific Northwest National Laboratory-TiO2SRM


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

Loader

Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y5 (1+) 19.4 5.3 6.4 25.2 8.3 8.6 31.8 9.8 10.7 15 15 15
y6 (1+) 12.5 4 5.9 14.9 7 4.1 19.4 8.1 7.2 15 15 15
y7 (1+) 17.7 8.4 8.6 21.2 9.5 9.4 27.6 12.7 12.7 15 15 15
sum 9.1 3.7 3.1 10.8 6.3 2.8 14.1 7.3 4.2 15 15 15


Additional Resources and Comments