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Overview Data source: UniProt

Official Gene Symbol Other Aliases
M6PR MPR46,MPRD
Sequence Length (AA) Molecular Weight (Da)
277 30993
Protein Name
Cation-dependent mannose-6-phosphate receptor
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MFPFYSCWRT GLLLLLLAVA VRESWQTEEK TCDLVGEKGK ESEKELALVK
60 70 80 90 100
RLKPLFNKSF ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE
110 120 130 140 150
TVVGRLNETH IFNGSNWIML IYKGGDEYDN HCGKEQRRAV VMISCNRHTL
160 170 180 190 200
ADNFNPVSEE RGKVQDCFYL FEMDSSLACS PEISHLSVGS ILLVTFASLV
210 220 230 240 250
AVYVVGGFLY QRLVVGAKGM EQFPHLAFWQ DLGNLVADGC DFVCRSKPRN
260 270 277
VPAAYRGVGD DQLGEESEER DDHLLPM

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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to view detailed assay information below
All other points link out to UniProt



Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-1308 Collapse assay details

Data source: Panorama

Official Gene Symbol
M6PR
Peptide Modified Sequence
LKPLFN[+1.0]K
Modification Type
Deamidated (N)
Protein - Site of Modification
57
Peptide - Site of Modification
6
Peptide Start
52
Peptide End
58
CPTAC ID
CPTAC-1308
Peptide Molecular Mass
859.5167
Species
Homo sapiens (Human)
Assay Type
Direct MRM
Matrix
Human ovarian tumor tissue digest
Submitting Laboratory
Johns Hopkins University
Submitting Lab PI
Daniel Chan, Hui Zhang, Zhen Zhang

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
Stable isotope-labeled peptides
Peptide Standard Purity
Crude (~60%)
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Accela 1250 Quaternary Low Pump
Column Packing
C18, 3 µm, 300 Å
Column Dimensions
1.0 mm I.D. x 15 cm
Flow Rate
50 µL/min

Assay Multiplexing Expand assay panel

Johns Hopkins University-D


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y5 (1+) 136.1 65.3 125 136.9 82.3 80.7 193 105.1 148.8 15 15 15
y3 (1+) 108.3 74.7 69.5 168.8 98.9 88 200.6 123.9 112.1 15 15 15
y2 (1+) 113.3 48.1 31.7 103.8 85 34.4 153.7 97.7 46.8 15 15 15
sum 114.9 26.3 29.6 128 48.3 37.8 172 55 48 15 15 15

Additional Resources and Comments