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Overview Data source: UniProt

Official Gene Symbol Other Aliases
ITGB8 N/A
Sequence Length (AA) Molecular Weight (Da)
769 85632
Protein Name
Integrin beta-8
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MCGSALAFFT AAFVCLQNDR RGPASFLWAA WVFSLVLGLG QGEDNRCASS
60 70 80 90 100
NAASCARCLA LGPECGWCVQ EDFISGGSRS ERCDIVSNLI SKGCSVDSIE
110 120 130 140 150
YPSVHVIIPT ENEINTQVTP GEVSIQLRPG AEANFMLKVH PLKKYPVDLY
160 170 180 190 200
YLVDVSASMH NNIEKLNSVG NDLSRKMAFF SRDFRLGFGS YVDKTVSPYI
210 220 230 240 250
SIHPERIHNQ CSDYNLDCMP PHGYIHVLSL TENITEFEKA VHRQKISGNI
260 270 280 290 300
DTPEGGFDAM LQAAVCESHI GWRKEAKRLL LVMTDQTSHL ALDSKLAGIV
310 320 330 340 350
VPNDGNCHLK NNVYVKSTTM EHPSLGQLSE KLIDNNINVI FAVQGKQFHW
360 370 380 390 400
YKDLLPLLPG TIAGEIESKA ANLNNLVVEA YQKLISEVKV QVENQVQGIY
410 420 430 440 450
FNITAICPDG SRKPGMEGCR NVTSNDEVLF NVTVTMKKCD VTGGKNYAII
460 470 480 490 500
KPIGFNETAK IHIHRNCSCQ CEDNRGPKGK CVDETFLDSK CFQCDENKCH
510 520 530 540 550
FDEDQFSSES CKSHKDQPVC SGRGVCVCGK CSCHKIKLGK VYGKYCEKDD
560 570 580 590 600
FSCPYHHGNL CAGHGECEAG RCQCFSGWEG DRCQCPSAAA QHCVNSKGQV
610 620 630 640 650
CSGRGTCVCG RCECTDPRSI GRFCEHCPTC YTACKENWNC MQCLHPHNLS
660 670 680 690 700
QAILDQCKTS CALMEQQHYV DQTSECFSSP SYLRIFFIIF IVTFLIGLLK
710 720 730 740 750
VLIIRQVILQ WNSNKIKSSS DYRVSASKKD KLILQSVCTR AVTYRREKPE
760 769
EIKMDISKLN AHETFRCNF

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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to view detailed assay information below
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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-1311 Collapse assay details

Data source: Panorama

Official Gene Symbol
ITGB8
Peptide Modified Sequence
NYAIIKPIGFN[+1.0]ETAK
Modification Type
Deamidated (N)
Protein - Site of Modification
456
Peptide - Site of Modification
11
Peptide Start
446
Peptide End
460
CPTAC ID
CPTAC-1311
Peptide Molecular Mass
1,678.8930
Species
Homo sapiens (Human)
Assay Type
Direct MRM
Matrix
Human ovarian tumor tissue digest
Submitting Laboratory
Johns Hopkins University
Submitting Lab PI
Daniel Chan, Hui Zhang, Zhen Zhang

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
TSQ Vantage
Internal Standard
Stable isotope-labeled peptides
Peptide Standard Purity
Crude (~60%)
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Accela 1250 Quaternary Low Pump
Column Packing
C18, 3 µm, 300 Å
Column Dimensions
1.0 mm I.D. x 15 cm
Flow Rate
50 µL/min

Assay Multiplexing Expand assay panel

Johns Hopkins University-D


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y9 (1+) 21.4 8.2 6.7 24 8.9 7.1 32.2 12.1 9.8 15 15 15
y7 (1+) 64.6 14.4 14.1 59 14.3 15.1 87.5 20.3 20.7 15 15 15
y13 (2+) 83.2 14.7 18.8 74.9 15.4 18.7 111.9 21.3 26.5 15 15 15
sum 22.9 4.9 8 25.5 6.4 7.3 34.3 8.1 10.8 15 15 15

Additional Resources and Comments