| Official Gene Symbol | Other Aliases |
|---|---|
| KRAS | KRAS2, RASK2 |
| Sequence Length (AA) | Molecular Weight (Da) |
|---|---|
| 189 | 21656 |
| Protein Name |
|---|
| GTPase KRas |
| Sources | |
|---|---|
|
UniProt PhosphoSitePlus ® GeneCards |
Human Protein Atlas |
| 10 | 20 | 30 | 40 | 50 |
| MTEYKLVVVG | AGGVGKSALT | IQLIQNHFVD | EYDPTIEDSY | RKQVVIDGET |
| 60 | 70 | 80 | 90 | 100 |
| CLLDILDTAG | QEEYSAMRDQ | YMRTGEGFLC | VFAINNTKSF | EDIHHYREQI |
| 110 | 120 | 130 | 140 | 150 |
| KRVKDSEDVP | MVLVGNKCDL | PSRTVDTKQA | QDLARSYGIP | FIETSAKTRQ |
| 160 | 170 | 180 | 189 | |
| RVEDAFYTLV | REIRQYRLKK | ISKEEKTPGC | VKIKKCIIM |
Data source: UniProt
Uniprot Database Entry PhosphoSitePlus ®
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Data source: Panorama
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mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours. Constance A Sobsey, Bjoern C Froehlich, Georgia Mitsa, Sahar Ibrahim, Robert Popp, Rene P Zahedi, Elza C de Bruin, Christoph H Borchers, Gerald Batist
Data source: Panorama
Pacific Northwest National Laboratory-DirectSRM2
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| b2 (1+) | 16.7 | 6.6 | 4.2 | 21.1 | 6.7 | 5.2 | 26.9 | 9.4 | 6.7 | 15 | 16 | 17 |
| b3 (1+) | 16.6 | 4.8 | 8.4 | 21 | 7.2 | 7.3 | 26.8 | 8.7 | 11.1 | 15 | 16 | 17 |
| y7 (1+) | 19 | 3.9 | 6.1 | 23.2 | 2.7 | 5.9 | 30 | 4.7 | 8.5 | 15 | 16 | 17 |
| y8 (1+) | 16.1 | 7 | 9.2 | 18 | 8.3 | 7.4 | 24.1 | 10.9 | 11.8 | 15 | 16 | 17 |
| y9 (1+) | 18.5 | 7.2 | 7.9 | 21.5 | 6.6 | 9.6 | 28.4 | 9.8 | 12.4 | 15 | 16 | 17 |
| sum | 14.9 | 1.9 | 2.4 | 17.4 | 1.7 | 2.6 | 22.9 | 2.5 | 3.5 | 15 | 16 | 17 |
Data source: Panorama
Data source: Panorama
Pacific Northwest National Laboratory-DirectSRM2
Data source: Panorama
Data source: Panorama
Retrieving Data
Data source: Panorama
| Average intra-assay CV (within day CV) |
Average inter-assay CV (between day CV) |
Total CV |
n= | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 26.4 | 10.1 | 13.3 | 21.4 | 12.9 | 14.2 | 34 | 16.4 | 19.5 | 15 | 15 | 15 |
| y6 (1+) | 22 | 11.5 | 8.5 | 29.3 | 16.2 | 9 | 36.6 | 19.9 | 12.4 | 15 | 15 | 15 |
| y3 (1+) | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0 | 0 | 0 |
| a2 (1+) | 4.4 | 6.9 | 3.9 | 7.3 | 12.2 | 7.6 | 8.5 | 14 | 8.5 | 15 | 15 | 15 |
| y4 (1+) | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0 | 0 | 0 |
| sum | 5.1 | 6 | 3.4 | 7.9 | 11.4 | 6.9 | 9.4 | 12.9 | 7.7 | 15 | 15 | 15 |
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