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Please include the following statement when referencing the CPTAC Assay Portal
We would like to acknowledge the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (assays.cancer.gov) for developing assays and establishing criteria for the assays described in this publication.

MUC16

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Available Assays

Overview Data source: UniProt

Official Gene Symbol Other Aliases
MUC16 CA125
Sequence Length (AA) Molecular Weight (Da)
14507 1519175
Protein Name
Mucin-16
Sources
UniProt
PhosphoSitePlus ®
GeneCards 		Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MLKPSGLPGS SSPTRSLMTG SRSTKATPEM DSGLTGATLS PKTSTGAIVV
60 70 80 90 100
TEHTLPFTSP DKTLASPTSS VVGRTTQSLG VMSSALPEST SRGMTHSEQR
110 120 130 140 150
TSPSLSPQVN GTPSRNYPAT SMVSGLSSPR TRTSSTEGNF TKEASTYTLT
160 170 180 190 200
VETTSGPVTE KYTVPTETST TEGDSTETPW DTRYIPVKIT SPMKTFADST
210 220 230 240 250
ASKENAPVSM TPAETTVTDS HTPGRTNPSF GTLYSSFLDL SPKGTPNSRG
260 270 280 290 300
ETSLELILST TGYPFSSPEP GSAGHSRIST SAPLSSSASV LDNKISETSI
310 320 330 340 350
FSGQSLTSPL SPGVPEARAS TMPNSAIPFS MTLSNAETSA ERVRSTISSL
360 370 380 390 400
GTPSISTKQT AETILTFHAF AETMDIPSTH IAKTLASEWL GSPGTLGGTS
410 420 430 440 450
TSALTTTSPS TTLVSEETNT HHSTSGKETE GTLNTSMTPL ETSAPGEESE
460 470 480 490 500
MTATLVPTLG FTTLDSKIRS PSQVSSSHPT RELRTTGSTS GRQSSSTAAH
510 520 530 540 550
GSSDILRATT SSTSKASSWT SESTAQQFSE PQHTQWVETS PSMKTERPPA
560 570 580 590 600
STSVAAPITT SVPSVVSGFT TLKTSSTKGI WLEETSADTL IGESTAGPTT
610 620 630 640 650
HQFAVPTGIS MTGGSSTRGS QGTTHLLTRA TASSETSADL TLATNGVPVS
660 670 680 690 700
VSPAVSKTAA GSSPPGGTKP SYTMVSSVIP ETSSLQSSAF REGTSLGLTP
710 720 730 740 750
LNTRHPFSSP EPDSAGHTKI STSIPLLSSA SVLEDKVSAT STFSHHKATS
760 770 780 790 800
SITTGTPEIS TKTKPSSAVL SSMTLSNAAT SPERVRNATS PLTHPSPSGE
810 820 830 840 850
ETAGSVLTLS TSAETTDSPN IHPTGTLTSE SSESPSTLSL PSVSGVKTTF
860 870 880 890 900
SSSTPSTHLF TSGEETEETS NPSVSQPETS VSRVRTTLAS TSVPTPVFPT
910 920 930 940 950
MDTWPTRSAQ FSSSHLVSEL RATSSTSVTN STGSALPKIS HLTGTATMSQ
960 970 980 990 1000
TNRDTFNDSA APQSTTWPET SPRFKTGLPS ATTTVSTSAT SLSATVMVSK
1010 1020 1030 1040 1050
FTSPATSSME ATSIREPSTT ILTTETTNGP GSMAVASTNI PIGKGYITEG
1060 1070 1080 1090 1100
RLDTSHLPIG TTASSETSMD FTMAKESVSM SVSPSQSMDA AGSSTPGRTS
1110 1120 1130 1140 1150
QFVDTFSDDV YHLTSREITI PRDGTSSALT PQMTATHPPS PDPGSARSTW
1160 1170 1180 1190 1200
LGILSSSPSS PTPKVTMSST FSTQRVTTSM IMDTVETSRW NMPNLPSTTS
1210 1220 1230 1240 1250
LTPSNIPTSG AIGKSTLVPL DTPSPATSLE ASEGGLPTLS TYPESTNTPS
1260 1270 1280 1290 1300
IHLGAHASSE SPSTIKLTMA SVVKPGSYTP LTFPSIETHI HVSTARMAYS
1310 1320 1330 1340 1350
SGSSPEMTAP GETNTGSTWD PTTYITTTDP KDTSSAQVST PHSVRTLRTT
1360 1370 1380 1390 1400
ENHPKTESAT PAAYSGSPKI SSSPNLTSPA TKAWTITDTT EHSTQLHYTK
1410 1420 1430 1440 1450
LAEKSSGFET QSAPGPVSVV IPTSPTIGSS TLELTSDVPG EPLVLAPSEQ
1460 1470 1480 1490 1500
TTITLPMATW LSTSLTEEMA STDLDISSPS SPMSTFAIFP PMSTPSHELS
1510 1520 1530 1540 1550
KSEADTSAIR NTDSTTLDQH LGIRSLGRTG DLTTVPITPL TTTWTSVIEH
1560 1570 1580 1590 1600
STQAQDTLSA TMSPTHVTQS LKDQTSIPAS ASPSHLTEVY PELGTQGRSS
1610 1620 1630 1640 1650
SEATTFWKPS TDTLSREIET GPTNIQSTPP MDNTTTGSSS SGVTLGIAHL
1660 1670 1680 1690 1700
PIGTSSPAET STNMALERRS STATVSMAGT MGLLVTSAPG RSISQSLGRV
1710 1720 1730 1740 1750
SSVLSESTTE GVTDSSKGSS PRLNTQGNTA LSSSLEPSYA EGSQMSTSIP
1760 1770 1780 1790 1800
LTSSPTTPDV EFIGGSTFWT KEVTTVMTSD ISKSSARTES SSATLMSTAL
1810 1820 1830 1840 1850
GSTENTGKEK LRTASMDLPS PTPSMEVTPW ISLTLSNAPN TTDSLDLSHG
1860 1870 1880 1890 1900
VHTSSAGTLA TDRSLNTGVT RASRLENGSD TSSKSLSMGN STHTSMTYTE
1910 1920 1930 1940 1950
KSEVSSSIHP RPETSAPGAE TTLTSTPGNR AISLTLPFSS IPVEEVISTG
1960 1970 1980 1990 2000
ITSGPDINSA PMTHSPITPP TIVWTSTGTI EQSTQPLHAV SSEKVSVQTQ
2010 2020 2030 2040 2050
STPYVNSVAV SASPTHENSV SSGSSTSSPY SSASLESLDS TISRRNAITS
2060 2070 2080 2090 2100
WLWDLTTSLP TTTWPSTSLS EALSSGHSGV SNPSSTTTEF PLFSAASTSA
2110 2120 2130 2140 2150
AKQRNPETET HGPQNTAAST LNTDASSVTG LSETPVGASI SSEVPLPMAI
2160 2170 2180 2190 2200
TSRSDVSGLT SESTANPSLG TASSAGTKLT RTISLPTSES LVSFRMNKDP
2210 2220 2230 2240 2250
WTVSIPLGSH PTTNTETSIP VNSAGPPGLS TVASDVIDTP SDGAESIPTV
2260 2270 2280 2290 2300
SFSPSPDTEV TTISHFPEKT THSFRTISSL THELTSRVTP IPGDWMSSAM
2310 2320 2330 2340 2350
STKPTGASPS ITLGERRTIT SAAPTTSPIV LTASFTETST VSLDNETTVK
2360 2370 2380 2390 2400
TSDILDARKT NELPSDSSSS SDLINTSIAS STMDVTKTAS ISPTSISGMT
2410 2420 2430 2440 2450
ASSSPSLFSS DRPQVPTSTT ETNTATSPSV SSNTYSLDGG SNVGGTPSTL
2460 2470 2480 2490 2500
PPFTITHPVE TSSALLAWSR PVRTFSTMVS TDTASGENPT SSNSVVTSVP
2510 2520 2530 2540 2550
APGTWTSVGS TTDLPAMGFL KTSPAGEAHS LLASTIEPAT AFTPHLSAAV
2560 2570 2580 2590 2600
VTGSSATSEA SLLTTSESKA IHSSPQTPTT PTSGANWETS ATPESLLVVT
2610 2620 2630 2640 2650
ETSDTTLTSK ILVTDTILFS TVSTPPSKFP STGTLSGASF PTLLPDTPAI
2660 2670 2680 2690 2700
PLTATEPTSS LATSFDSTPL VTIASDSLGT VPETTLTMSE TSNGDALVLK
2710 2720 2730 2740 2750
TVSNPDRSIP GITIQGVTES PLHPSSTSPS KIVAPRNTTY EGSITVALST
2760 2770 2780 2790 2800
LPAGTTGSLV FSQSSENSET TALVDSSAGL ERASVMPLTT GSQGMASSGG
2810 2820 2830 2840 2850
IRSGSTHSTG TKTFSSLPLT MNPGEVTAMS EITTNRLTAT QSTAPKGIPV
2860 2870 2880 2890 2900
KPTSAESGLL TPVSASSSPS KAFASLTTAP PTWGIPQSTL TFEFSEVPSL
2910 2920 2930 2940 2950
DTKSASLPTP GQSLNTIPDS DASTASSSLS KSPEKNPRAR MMTSTKAISA
2960 2970 2980 2990 3000
SSFQSTGFTE TPEGSASPSM AGHEPRVPTS GTGDPRYASE SMSYPDPSKA
3010 3020 3030 3040 3050
SSAMTSTSLA SKLTTLFSTG QAARSGSSSS PISLSTEKET SFLSPTASTS
3060 3070 3080 3090 3100
RKTSLFLGPS MARQPNILVH LQTSALTLSP TSTLNMSQEE PPELTSSQTI
3110 3120 3130 3140 3150
AEEEGTTAET QTLTFTPSET PTSLLPVSSP TEPTARRKSS PETWASSISV
3160 3170 3180 3190 3200
PAKTSLVETT DGTLVTTIKM SSQAAQGNST WPAPAEETGS SPAGTSPGSP
3210 3220 3230 3240 3250
EMSTTLKIMS SKEPSISPEI RSTVRNSPWK TPETTVPMET TVEPVTLQST
3260 3270 3280 3290 3300
ALGSGSTSIS HLPTGTTSPT KSPTENMLAT ERVSLSPSPP EAWTNLYSGT
3310 3320 3330 3340 3350
PGGTRQSLAT MSSVSLESPT ARSITGTGQQ SSPELVSKTT GMEFSMWHGS
3360 3370 3380 3390 3400
TGGTTGDTHV SLSTSSNILE DPVTSPNSVS SLTDKSKHKT ETWVSTTAIP
3410 3420 3430 3440 3450
STVLNNKIMA AEQQTSRSVD EAYSSTSSWS DQTSGSDITL GASPDVTNTL
3460 3470 3480 3490 3500
YITSTAQTTS LVSLPSGDQG ITSLTNPSGG KTSSASSVTS PSIGLETLRA
3510 3520 3530 3540 3550
NVSAVKSDIA PTAGHLSQTS SPAEVSILDV TTAPTPGIST TITTMGTNSI
3560 3570 3580 3590 3600
STTTPNPEVG MSTMDSTPAT ERRTTSTEHP STWSSTAASD SWTVTDMTSN
3610 3620 3630 3640 3650
LKVARSPGTI STMHTTSFLA SSTELDSMST PHGRITVIGT SLVTPSSDAS
3660 3670 3680 3690 3700
AVKTETSTSE RTLSPSDTTA STPISTFSRV QRMSISVPDI LSTSWTPSST
3710 3720 3730 3740 3750
EAEDVPVSMV STDHASTKTD PNTPLSTFLF DSLSTLDWDT GRSLSSATAT
3760 3770 3780 3790 3800
TSAPQGATTP QELTLETMIS PATSQLPFSI GHITSAVTPA AMARSSGVTF
3810 3820 3830 3840 3850
SRPDPTSKKA EQTSTQLPTT TSAHPGQVPR SAATTLDVIP HTAKTPDATF
3860 3870 3880 3890 3900
QRQGQTALTT EARATSDSWN EKEKSTPSAP WITEMMNSVS EDTIKEVTSS
3910 3920 3930 3940 3950
SSVLRTLNTL DINLESGTTS SPSWKSSPYE RIAPSESTTD KEAIHPSTNT
3960 3970 3980 3990 4000
VETTGWVTSS EHASHSTIPA HSASSKLTSP VVTTSTREQA IVSMSTTTWP
4010 4020 4030 4040 4050
ESTRARTEPN SFLTIELRDV SPYMDTSSTT QTSIISSPGS TAITKGPRTE
4060 4070 4080 4090 4100
ITSSKRISSS FLAQSMRSSD SPSEAITRLS NFPAMTESGG MILAMQTSPP
4110 4120 4130 4140 4150
GATSLSAPTL DTSATASWTG TPLATTQRFT YSEKTTLFSK GPEDTSQPSP
4160 4170 4180 4190 4200
PSVEETSSSS SLVPIHATTS PSNILLTSQG HSPSSTPPVT SVFLSETSGL
4210 4220 4230 4240 4250
GKTTDMSRIS LEPGTSLPPN LSSTAGEALS TYEASRDTKA IHHSADTAVT
4260 4270 4280 4290 4300
NMEATSSEYS PIPGHTKPSK ATSPLVTSHI MGDITSSTSV FGSSETTEIE
4310 4320 4330 4340 4350
TVSSVNQGLQ ERSTSQVASS ATETSTVITH VSSGDATTHV TKTQATFSSG
4360 4370 4380 4390 4400
TSISSPHQFI TSTNTFTDVS TNPSTSLIMT ESSGVTITTQ TGPTGAATQG
4410 4420 4430 4440 4450
PYLLDTSTMP YLTETPLAVT PDFMQSEKTT LISKGPKDVS WTSPPSVAET
4460 4470 4480 4490 4500
SYPSSLTPFL VTTIPPATST LQGQHTSSPV SATSVLTSGL VKTTDMLNTS
4510 4520 4530 4540 4550
MEPVTNSPQN LNNPSNEILA TLAATTDIET IHPSINKAVT NMGTASSAHV
4560 4570 4580 4590 4600
LHSTLPVSSE PSTATSPMVP ASSMGDALAS ISIPGSETTD IEGEPTSSLT
4610 4620 4630 4640 4650
AGRKENSTLQ EMNSTTESNI ILSNVSVGAI TEATKMEVPS FDATFIPTPA
4660 4670 4680 4690 4700
QSTKFPDIFS VASSRLSNSP PMTISTHMTT TQTGSSGATS KIPLALDTST
4710 4720 4730 4740 4750
LETSAGTPSV VTEGFAHSKI TTAMNNDVKD VSQTNPPFQD EASSPSSQAP
4760 4770 4780 4790 4800
VLVTTLPSSV AFTPQWHSTS SPVSMSSVLT SSLVKTAGKV DTSLETVTSS
4810 4820 4830 4840 4850
PQSMSNTLDD ISVTSAATTD IETTHPSINT VVTNVGTTGS AFESHSTVSA
4860 4870 4880 4890 4900
YPEPSKVTSP NVTTSTMEDT TISRSIPKSS KTTRTETETT SSLTPKLRET
4910 4920 4930 4940 4950
SISQEITSST ETSTVPYKEL TGATTEVSRT DVTSSSSTSF PGPDQSTVSL
4960 4970 4980 4990 5000
DISTETNTRL STSPIMTESA EITITTQTGP HGATSQDTFT MDPSNTTPQA
5010 5020 5030 5040 5050
GIHSAMTHGF SQLDVTTLMS RIPQDVSWTS PPSVDKTSSP SSFLSSPAMT
5060 5070 5080 5090 5100
TPSLISSTLP EDKLSSPMTS LLTSGLVKIT DILRTRLEPV TSSLPNFSST
5110 5120 5130 5140 5150
SDKILATSKD SKDTKEIFPS INTEETNVKA NNSGHESHSP ALADSETPKA
5160 5170 5180 5190 5200
TTQMVITTTV GDPAPSTSMP VHGSSETTNI KREPTYFLTP RLRETSTSQE
5210 5220 5230 5240 5250
SSFPTDTSFL LSKVPTGTIT EVSSTGVNSS SKISTPDHDK STVPPDTFTG
5260 5270 5280 5290 5300
EIPRVFTSSI KTKSAEMTIT TQASPPESAS HSTLPLDTST TLSQGGTHST
5310 5320 5330 5340 5350
VTQGFPYSEV TTLMGMGPGN VSWMTTPPVE ETSSVSSLMS SPAMTSPSPV
5360 5370 5380 5390 5400
SSTSPQSIPS SPLPVTALPT SVLVTTTDVL GTTSPESVTS SPPNLSSITH
5410 5420 5430 5440 5450
ERPATYKDTA HTEAAMHHST NTAVTNVGTS GSGHKSQSSV LADSETSKAT
5460 5470 5480 5490 5500
PLMSTTSTLG DTSVSTSTPN ISQTNQIQTE PTASLSPRLR ESSTSEKTSS
5510 5520 5530 5540 5550
TTETNTAFSY VPTGAITQAS RTEISSSRTS ISDLDRPTIA PDISTGMITR
5560 5570 5580 5590 5600
LFTSPIMTKS AEMTVTTQTT TPGATSQGIL PWDTSTTLFQ GGTHSTVSQG
5610 5620 5630 5640 5650
FPHSEITTLR SRTPGDVSWM TTPPVEETSS GFSLMSPSMT SPSPVSSTSP
5660 5670 5680 5690 5700
ESIPSSPLPV TALLTSVLVT TTNVLGTTSP EPVTSSPPNL SSPTQERLTT
5710 5720 5730 5740 5750
YKDTAHTEAM HASMHTNTAV ANVGTSISGH ESQSSVPADS HTSKATSPMG
5760 5770 5780 5790 5800
ITFAMGDTSV STSTPAFFET RIQTESTSSL IPGLRDTRTS EEINTVTETS
5810 5820 5830 5840 5850
TVLSEVPTTT TTEVSRTEVI TSSRTTISGP DHSKMSPYIS TETITRLSTF
5860 5870 5880 5890 5900
PFVTGSTEMA ITNQTGPIGT ISQATLTLDT SSTASWEGTH SPVTQRFPHS
5910 5920 5930 5940 5950
EETTTMSRST KGVSWQSPPS VEETSSPSSP VPLPAITSHS SLYSAVSGSS
5960 5970 5980 5990 6000
PTSALPVTSL LTSGRRKTID MLDTHSELVT SSLPSASSFS GEILTSEAST
6010 6020 6030 6040 6050
NTETIHFSEN TAETNMGTTN SMHKLHSSVS IHSQPSGHTP PKVTGSMMED
6060 6070 6080 6090 6100
AIVSTSTPGS PETKNVDRDS TSPLTPELKE DSTALVMNST TESNTVFSSV
6110 6120 6130 6140 6150
SLDAATEVSR AEVTYYDPTF MPASAQSTKS PDISPEASSS HSNSPPLTIS
6160 6170 6180 6190 6200
THKTIATQTG PSGVTSLGQL TLDTSTIATS AGTPSARTQD FVDSETTSVM
6210 6220 6230 6240 6250
NNDLNDVLKT SPFSAEEANS LSSQAPLLVT TSPSPVTSTL QEHSTSSLVS
6260 6270 6280 6290 6300
VTSVPTPTLA KITDMDTNLE PVTRSPQNLR NTLATSEATT DTHTMHPSIN
6310 6320 6330 6340 6350
TAVANVGTTS SPNEFYFTVS PDSDPYKATS AVVITSTSGD SIVSTSMPRS
6360 6370 6380 6390 6400
SAMKKIESET TFSLIFRLRE TSTSQKIGSS SDTSTVFDKA FTAATTEVSR
6410 6420 6430 6440 6450
TELTSSSRTS IQGTEKPTMS PDTSTRSVTM LSTFAGLTKS EERTIATQTG
6460 6470 6480 6490 6500
PHRATSQGTL TWDTSITTSQ AGTHSAMTHG FSQLDLSTLT SRVPEYISGT
6510 6520 6530 6540 6550
SPPSVEKTSS SSSLLSLPAI TSPSPVPTTL PESRPSSPVH LTSLPTSGLV
6560 6570 6580 6590 6600
KTTDMLASVA SLPPNLGSTS HKIPTTSEDI KDTEKMYPST NIAVTNVGTT
6610 6620 6630 6640 6650
TSEKESYSSV PAYSEPPKVT SPMVTSFNIR DTIVSTSMPG SSEITRIEME
6660 6670 6680 6690 6700
STFSLAHGLK GTSTSQDPIV STEKSAVLHK LTTGATETSR TEVASSRRTS
6710 6720 6730 6740 6750
IPGPDHSTES PDISTEVIPS LPISLGITES SNMTIITRTG PPLGSTSQGT
6760 6770 6780 6790 6800
FTLDTPTTSS RAGTHSMATQ EFPHSEMTTV MNKDPEILSW TIPPSIEKTS
6810 6820 6830 6840 6850
FSSSLMPSPA MTSPPVSSTL PKTIHTTPSP MTSLLTPSLV MTTDTLGTSP
6860 6870 6880 6890 6900
EPTTSSPPNL SSTSHEILTT DEDTTAIEAM HPSTSTAATN VETTSSGHGS
6910 6920 6930 6940 6950
QSSVLADSEK TKATAPMDTT STMGHTTVST SMSVSSETTK IKRESTYSLT
6960 6970 6980 6990 7000
PGLRETSISQ NASFSTDTSI VLSEVPTGTT AEVSRTEVTS SGRTSIPGPS
7010 7020 7030 7040 7050
QSTVLPEIST RTMTRLFASP TMTESAEMTI PTQTGPSGST SQDTLTLDTS
7060 7070 7080 7090 7100
TTKSQAKTHS TLTQRFPHSE MTTLMSRGPG DMSWQSSPSL ENPSSLPSLL
7110 7120 7130 7140 7150
SLPATTSPPP ISSTLPVTIS SSPLPVTSLL TSSPVTTTDM LHTSPELVTS
7160 7170 7180 7190 7200
SPPKLSHTSD ERLTTGKDTT NTEAVHPSTN TAASNVEIPS SGHESPSSAL
7210 7220 7230 7240 7250
ADSETSKATS PMFITSTQED TTVAISTPHF LETSRIQKES ISSLSPKLRE
7260 7270 7280 7290 7300
TGSSVETSSA IETSAVLSEV SIGATTEISR TEVTSSSRTS ISGSAESTML
7310 7320 7330 7340 7350
PEISTTRKII KFPTSPILAE SSEMTIKTQT SPPGSTSEST FTLDTSTTPS
7360 7370 7380 7390 7400
LVITHSTMTQ RLPHSEITTL VSRGAGDVPR PSSLPVEETS PPSSQLSLSA
7410 7420 7430 7440 7450
MISPSPVSST LPASSHSSSA SVTSLLTPGQ VKTTEVLDAS AEPETSSPPS
7460 7470 7480 7490 7500
LSSTSVEILA TSEVTTDTEK IHPFSNTAVT KVGTSSSGHE SPSSVLPDSE
7510 7520 7530 7540 7550
TTKATSAMGT ISIMGDTSVS TLTPALSNTR KIQSEPASSL TTRLRETSTS
7560 7570 7580 7590 7600
EETSLATEAN TVLSKVSTGA TTEVSRTEAI SFSRTSMSGP EQSTMSQDIS
7610 7620 7630 7640 7650
IGTIPRISAS SVLTESAKMT ITTQTGPSES TLESTLNLNT ATTPSWVETH
7660 7670 7680 7690 7700
SIVIQGFPHP EMTTSMGRGP GGVSWPSPPF VKETSPPSSP LSLPAVTSPH
7710 7720 7730 7740 7750
PVSTTFLAHI PPSPLPVTSL LTSGPATTTD ILGTSTEPGT SSSSSLSTTS
7760 7770 7780 7790 7800
HERLTTYKDT AHTEAVHPST NTGGTNVATT SSGYKSQSSV LADSSPMCTT
7810 7820 7830 7840 7850
STMGDTSVLT STPAFLETRR IQTELASSLT PGLRESSGSE GTSSGTKMST
7860 7870 7880 7890 7900
VLSKVPTGAT TEISKEDVTS IPGPAQSTIS PDISTRTVSW FSTSPVMTES
7910 7920 7930 7940 7950
AEITMNTHTS PLGATTQGTS TLDTSSTTSL TMTHSTISQG FSHSQMSTLM
7960 7970 7980 7990 8000
RRGPEDVSWM SPPLLEKTRP SFSLMSSPAT TSPSPVSSTL PESISSSPLP
8010 8020 8030 8040 8050
VTSLLTSGLA KTTDMLHKSS EPVTNSPANL SSTSVEILAT SEVTTDTEKT
8060 8070 8080 8090 8100
HPSSNRTVTD VGTSSSGHES TSFVLADSQT SKVTSPMVIT STMEDTSVST
8110 8120 8130 8140 8150
STPGFFETSR IQTEPTSSLT LGLRKTSSSE GTSLATEMST VLSGVPTGAT
8160 8170 8180 8190 8200
AEVSRTEVTS SSRTSISGFA QLTVSPETST ETITRLPTSS IMTESAEMMI
8210 8220 8230 8240 8250
KTQTDPPGST PESTHTVDIS TTPNWVETHS TVTQRFSHSE MTTLVSRSPG
8260 8270 8280 8290 8300
DMLWPSQSSV EETSSASSLL SLPATTSPSP VSSTLVEDFP SASLPVTSLL
8310 8320 8330 8340 8350
NPGLVITTDR MGISREPGTS STSNLSSTSH ERLTTLEDTV DTEDMQPSTH
8360 8370 8380 8390 8400
TAVTNVRTSI SGHESQSSVL SDSETPKATS PMGTTYTMGE TSVSISTSDF
8410 8420 8430 8440 8450
FETSRIQIEP TSSLTSGLRE TSSSERISSA TEGSTVLSEV PSGATTEVSR
8460 8470 8480 8490 8500
TEVISSRGTS MSGPDQFTIS PDISTEAITR LSTSPIMTES AESAITIETG
8510 8520 8530 8540 8550
SPGATSEGTL TLDTSTTTFW SGTHSTASPG FSHSEMTTLM SRTPGDVPWP
8560 8570 8580 8590 8600
SLPSVEEASS VSSSLSSPAM TSTSFFSTLP ESISSSPHPV TALLTLGPVK
8610 8620 8630 8640 8650
TTDMLRTSSE PETSSPPNLS STSAEILATS EVTKDREKIH PSSNTPVVNV
8660 8670 8680 8690 8700
GTVIYKHLSP SSVLADLVTT KPTSPMATTS TLGNTSVSTS TPAFPETMMT
8710 8720 8730 8740 8750
QPTSSLTSGL REISTSQETS SATERSASLS GMPTGATTKV SRTEALSLGR
8760 8770 8780 8790 8800
TSTPGPAQST ISPEISTETI TRISTPLTTT GSAEMTITPK TGHSGASSQG
8810 8820 8830 8840 8850
TFTLDTSSRA SWPGTHSAAT HRSPHSGMTT PMSRGPEDVS WPSRPSVEKT
8860 8870 8880 8890 8900
SPPSSLVSLS AVTSPSPLYS TPSESSHSSP LRVTSLFTPV MMKTTDMLDT
8910 8920 8930 8940 8950
SLEPVTTSPP SMNITSDESL ATSKATMETE AIQLSENTAV TQMGTISARQ
8960 8970 8980 8990 9000
EFYSSYPGLP EPSKVTSPVV TSSTIKDIVS TTIPASSEIT RIEMESTSTL
9010 9020 9030 9040 9050
TPTPRETSTS QEIHSATKPS TVPYKALTSA TIEDSMTQVM SSSRGPSPDQ
9060 9070 9080 9090 9100
STMSQDISTE VITRLSTSPI KTESTEMTIT TQTGSPGATS RGTLTLDTST
9110 9120 9130 9140 9150
TFMSGTHSTA SQGFSHSQMT ALMSRTPGDV PWLSHPSVEE ASSASFSLSS
9160 9170 9180 9190 9200
PVMTSSSPVS STLPDSIHSS SLPVTSLLTS GLVKTTELLG TSSEPETSSP
9210 9220 9230 9240 9250
PNLSSTSAEI LAITEVTTDT EKLEMTNVVT SGYTHESPSS VLADSVTTKA
9260 9270 9280 9290 9300
TSSMGITYPT GDTNVLTSTP AFSDTSRIQT KSKLSLTPGL METSISEETS
9310 9320 9330 9340 9350
SATEKSTVLS SVPTGATTEV SRTEAISSSR TSIPGPAQST MSSDTSMETI
9360 9370 9380 9390 9400
TRISTPLTRK ESTDMAITPK TGPSGATSQG TFTLDSSSTA SWPGTHSATT
9410 9420 9430 9440 9450
QRFPQSVVTT PMSRGPEDVS WPSPLSVEKN SPPSSLVSSS SVTSPSPLYS
9460 9470 9480 9490 9500
TPSGSSHSSP VPVTSLFTSI MMKATDMLDA SLEPETTSAP NMNITSDESL
9510 9520 9530 9540 9550
AASKATTETE AIHVFENTAA SHVETTSATE ELYSSSPGFS EPTKVISPVV
9560 9570 9580 9590 9600
TSSSIRDNMV STTMPGSSGI TRIEIESMSS LTPGLRETRT SQDITSSTET
9610 9620 9630 9640 9650
STVLYKMPSG ATPEVSRTEV MPSSRTSIPG PAQSTMSLDI SDEVVTRLST
9660 9670 9680 9690 9700
SPIMTESAEI TITTQTGYSL ATSQVTLPLG TSMTFLSGTH STMSQGLSHS
9710 9720 9730 9740 9750
EMTNLMSRGP ESLSWTSPRF VETTRSSSSL TSLPLTTSLS PVSSTLLDSS
9760 9770 9780 9790 9800
PSSPLPVTSL ILPGLVKTTE VLDTSSEPKT SSSPNLSSTS VEIPATSEIM
9810 9820 9830 9840 9850
TDTEKIHPSS NTAVAKVRTS SSVHESHSSV LADSETTITI PSMGITSAVD
9860 9870 9880 9890 9900
DTTVFTSNPA FSETRRIPTE PTFSLTPGFR ETSTSEETTS ITETSAVLYG
9910 9920 9930 9940 9950
VPTSATTEVS MTEIMSSNRI HIPDSDQSTM SPDIITEVIT RLSSSSMMSE
9960 9970 9980 9990 10000
STQMTITTQK SSPGATAQST LTLATTTAPL ARTHSTVPPR FLHSEMTTLM
10010 10020 10030 10040 10050
SRSPENPSWK SSLFVEKTSS SSSLLSLPVT TSPSVSSTLP QSIPSSSFSV
10060 10070 10080 10090 10100
TSLLTPGMVK TTDTSTEPGT SLSPNLSGTS VEILAASEVT TDTEKIHPSS
10110 10120 10130 10140 10150
SMAVTNVGTT SSGHELYSSV SIHSEPSKAT YPVGTPSSMA ETSISTSMPA
10160 10170 10180 10190 10200
NFETTGFEAE PFSHLTSGFR KTNMSLDTSS VTPTNTPSSP GSTHLLQSSK
10210 10220 10230 10240 10250
TDFTSSAKTS SPDWPPASQY TEIPVDIITP FNASPSITES TGITSFPESR
10260 10270 10280 10290 10300
FTMSVTESTH HLSTDLLPSA ETISTGTVMP SLSEAMTSFA TTGVPRAISG
10310 10320 10330 10340 10350
SGSPFSRTES GPGDATLSTI AESLPSSTPV PFSSSTFTTT DSSTIPALHE
10360 10370 10380 10390 10400
ITSSSATPYR VDTSLGTESS TTEGRLVMVS TLDTSSQPGR TSSSPILDTR
10410 10420 10430 10440 10450
MTESVELGTV TSAYQVPSLS TRLTRTDGIM EHITKIPNEA AHRGTIRPVK
10460 10470 10480 10490 10500
GPQTSTSPAS PKGLHTGGTK RMETTTTALK TTTTALKTTS RATLTTSVYT
10510 10520 10530 10540 10550
PTLGTLTPLN ASMQMASTIP TEMMITTPYV FPDVPETTSS LATSLGAETS
10560 10570 10580 10590 10600
TALPRTTPSV FNRESETTAS LVSRSGAERS PVIQTLDVSS SEPDTTASWV
10610 10620 10630 10640 10650
IHPAETIPTV SKTTPNFFHS ELDTVSSTAT SHGADVSSAI PTNISPSELD
10660 10670 10680 10690 10700
ALTPLVTISG TDTSTTFPTL TKSPHETETR TTWLTHPAET SSTIPRTIPN
10710 10720 10730 10740 10750
FSHHESDATP SIATSPGAET SSAIPIMTVS PGAEDLVTSQ VTSSGTDRNM
10760 10770 10780 10790 10800
TIPTLTLSPG EPKTIASLVT HPEAQTSSAI PTSTISPAVS RLVTSMVTSL
10810 10820 10830 10840 10850
AAKTSTTNRA LTNSPGEPAT TVSLVTHPAQ TSPTVPWTTS IFFHSKSDTT
10860 10870 10880 10890 10900
PSMTTSHGAE SSSAVPTPTV STEVPGVVTP LVTSSRAVIS TTIPILTLSP
10910 10920 10930 10940 10950
GEPETTPSMA TSHGEEASSA IPTPTVSPGV PGVVTSLVTS SRAVTSTTIP
10960 10970 10980 10990 11000
ILTFSLGEPE TTPSMATSHG TEAGSAVPTV LPEVPGMVTS LVASSRAVTS
11010 11020 11030 11040 11050
TTLPTLTLSP GEPETTPSMA TSHGAEASST VPTVSPEVPG VVTSLVTSSS
11060 11070 11080 11090 11100
GVNSTSIPTL ILSPGELETT PSMATSHGAE ASSAVPTPTV SPGVSGVVTP
11110 11120 11130 11140 11150
LVTSSRAVTS TTIPILTLSS SEPETTPSMA TSHGVEASSA VLTVSPEVPG
11160 11170 11180 11190 11200
MVTSLVTSSR AVTSTTIPTL TISSDEPETT TSLVTHSEAK MISAIPTLAV
11210 11220 11230 11240 11250
SPTVQGLVTS LVTSSGSETS AFSNLTVASS QPETIDSWVA HPGTEASSVV
11260 11270 11280 11290 11300
PTLTVSTGEP FTNISLVTHP AESSSTLPRT TSRFSHSELD TMPSTVTSPE
11310 11320 11330 11340 11350
AESSSAISTT ISPGIPGVLT SLVTSSGRDI SATFPTVPES PHESEATASW
11360 11370 11380 11390 11400
VTHPAVTSTT VPRTTPNYSH SEPDTTPSIA TSPGAEATSD FPTITVSPDV
11410 11420 11430 11440 11450
PDMVTSQVTS SGTDTSITIP TLTLSSGEPE TTTSFITYSE THTSSAIPTL
11460 11470 11480 11490 11500
PVSPGASKML TSLVISSGTD STTTFPTLTE TPYEPETTAI QLIHPAETNT
11510 11520 11530 11540 11550
MVPRTTPKFS HSKSDTTLPV AITSPGPEAS SAVSTTTISP DMSDLVTSLV
11560 11570 11580 11590 11600
PSSGTDTSTT FPTLSETPYE PETTATWLTH PAETSTTVSG TIPNFSHRGS
11610 11620 11630 11640 11650
DTAPSMVTSP GVDTRSGVPT TTIPPSIPGV VTSQVTSSAT DTSTAIPTLT
11660 11670 11680 11690 11700
PSPGEPETTA SSATHPGTQT GFTVPIRTVP SSEPDTMASW VTHPPQTSTP
11710 11720 11730 11740 11750
VSRTTSSFSH SSPDATPVMA TSPRTEASSA VLTTISPGAP EMVTSQITSS
11760 11770 11780 11790 11800
GAATSTTVPT LTHSPGMPET TALLSTHPRT ETSKTFPAST VFPQVSETTA
11810 11820 11830 11840 11850
SLTIRPGAET STALPTQTTS SLFTLLVTGT SRVDLSPTAS PGVSAKTAPL
11860 11870 11880 11890 11900
STHPGTETST MIPTSTLSLG LLETTGLLAT SSSAETSTST LTLTVSPAVS
11910 11920 11930 11940 11950
GLSSASITTD KPQTVTSWNT ETSPSVTSVG PPEFSRTVTG TTMTLIPSEM
11960 11970 11980 11990 12000
PTPPKTSHGE GVSPTTILRT TMVEATNLAT TGSSPTVAKT TTTFNTLAGS
12010 12020 12030 12040 12050
LFTPLTTPGM STLASESVTS RTSYNHRSWI STTSSYNRRY WTPATSTPVT
12060 12070 12080 12090 12100
STFSPGISTS SIPSSTAATV PFMVPFTLNF TITNLQYEED MRHPGSRKFN
12110 12120 12130 12140 12150
ATERELQGLL KPLFRNSSLE YLYSGCRLAS LRPEKDSSAT AVDAICTHRP
12160 12170 12180 12190 12200
DPEDLGLDRE RLYWELSNLT NGIQELGPYT LDRNSLYVNG FTHRSSMPTT
12210 12220 12230 12240 12250
STPGTSTVDV GTSGTPSSSP SPTTAGPLLM PFTLNFTITN LQYEEDMRRT
12260 12270 12280 12290 12300
GSRKFNTMES VLQGLLKPLF KNTSVGPLYS GCRLTLLRPE KDGAATGVDA
12310 12320 12330 12340 12350
ICTHRLDPKS PGLNREQLYW ELSKLTNDIE ELGPYTLDRN SLYVNGFTHQ
12360 12370 12380 12390 12400
SSVSTTSTPG TSTVDLRTSG TPSSLSSPTI MAAGPLLVPF TLNFTITNLQ
12410 12420 12430 12440 12450
YGEDMGHPGS RKFNTTERVL QGLLGPIFKN TSVGPLYSGC RLTSLRSEKD
12460 12470 12480 12490 12500
GAATGVDAIC IHHLDPKSPG LNRERLYWEL SQLTNGIKEL GPYTLDRNSL
12510 12520 12530 12540 12550
YVNGFTHRTS VPTSSTPGTS TVDLGTSGTP FSLPSPATAG PLLVLFTLNF
12560 12570 12580 12590 12600
TITNLKYEED MHRPGSRKFN TTERVLQTLL GPMFKNTSVG LLYSGCRLTL
12610 12620 12630 12640 12650
LRSEKDGAAT GVDAICTHRL DPKSPGVDRE QLYWELSQLT NGIKELGPYT
12660 12670 12680 12690 12700
LDRNSLYVNG FTHWIPVPTS STPGTSTVDL GSGTPSSLPS PTTAGPLLVP
12710 12720 12730 12740 12750
FTLNFTITNL KYEEDMHCPG SRKFNTTERV LQSLLGPMFK NTSVGPLYSG
12760 12770 12780 12790 12800
CRLTLLRSEK DGAATGVDAI CTHRLDPKSP GVDREQLYWE LSQLTNGIKE
12810 12820 12830 12840 12850
LGPYTLDRNS LYVNGFTHQT SAPNTSTPGT STVDLGTSGT PSSLPSPTSA
12860 12870 12880 12890 12900
GPLLVPFTLN FTITNLQYEE DMHHPGSRKF NTTERVLQGL LGPMFKNTSV
12910 12920 12930 12940 12950
GLLYSGCRLT LLRPEKNGAA TGMDAICSHR LDPKSPGLNR EQLYWELSQL
12960 12970 12980 12990 13000
THGIKELGPY TLDRNSLYVN GFTHRSSVAP TSTPGTSTVD LGTSGTPSSL
13010 13020 13030 13040 13050
PSPTTAVPLL VPFTLNFTIT NLQYGEDMRH PGSRKFNTTE RVLQGLLGPL
13060 13070 13080 13090 13100
FKNSSVGPLY SGCRLISLRS EKDGAATGVD AICTHHLNPQ SPGLDREQLY
13110 13120 13130 13140 13150
WQLSQMTNGI KELGPYTLDR NSLYVNGFTH RSSGLTTSTP WTSTVDLGTS
13160 13170 13180 13190 13200
GTPSPVPSPT TTGPLLVPFT LNFTITNLQY EENMGHPGSR KFNITESVLQ
13210 13220 13230 13240 13250
GLLKPLFKST SVGPLYSGCR LTLLRPEKDG VATRVDAICT HRPDPKIPGL
13260 13270 13280 13290 13300
DRQQLYWELS QLTHSITELG PYTLDRDSLY VNGFTQRSSV PTTSTPGTFT
13310 13320 13330 13340 13350
VQPETSETPS SLPGPTATGP VLLPFTLNFT ITNLQYEEDM RRPGSRKFNT
13360 13370 13380 13390 13400
TERVLQGLLM PLFKNTSVSS LYSGCRLTLL RPEKDGAATR VDAVCTHRPD
13410 13420 13430 13440 13450
PKSPGLDRER LYWKLSQLTH GITELGPYTL DRHSLYVNGF THQSSMTTTR
13460 13470 13480 13490 13500
TPDTSTMHLA TSRTPASLSG PMTASPLLVL FTINFTITNL RYEENMHHPG
13510 13520 13530 13540 13550
SRKFNTTERV LQGLLRPVFK NTSVGPLYSG CRLTLLRPKK DGAATKVDAI
13560 13570 13580 13590 13600
CTYRPDPKSP GLDREQLYWE LSQLTHSITE LGPYTLDRDS LYVNGFTQRS
13610 13620 13630 13640 13650
SVPTTSIPGT PTVDLGTSGT PVSKPGPSAA SPLLVLFTLN FTITNLRYEE
13660 13670 13680 13690 13700
NMQHPGSRKF NTTERVLQGL LRSLFKSTSV GPLYSGCRLT LLRPEKDGTA
13710 13720 13730 13740 13750
TGVDAICTHH PDPKSPRLDR EQLYWELSQL THNITELGPY ALDNDSLFVN
13760 13770 13780 13790 13800
GFTHRSSVST TSTPGTPTVY LGASKTPASI FGPSAASHLL ILFTLNFTIT
13810 13820 13830 13840 13850
NLRYEENMWP GSRKFNTTER VLQGLLRPLF KNTSVGPLYS GCRLTLLRPE
13860 13870 13880 13890 13900
KDGEATGVDA ICTHRPDPTG PGLDREQLYL ELSQLTHSIT ELGPYTLDRD
13910 13920 13930 13940 13950
SLYVNGFTHR SSVPTTSTGV VSEEPFTLNF TINNLRYMAD MGQPGSLKFN
13960 13970 13980 13990 14000
ITDNVMQHLL SPLFQRSSLG ARYTGCRVIA LRSVKNGAET RVDLLCTYLQ
14010 14020 14030 14040 14050
PLSGPGLPIK QVFHELSQQT HGITRLGPYS LDKDSLYLNG YNEPGPDEPP
14060 14070 14080 14090 14100
TTPKPATTFL PPLSEATTAM GYHLKTLTLN FTISNLQYSP DMGKGSATFN
14110 14120 14130 14140 14150
STEGVLQHLL RPLFQKSSMG PFYLGCQLIS LRPEKDGAAT GVDTTCTYHP
14160 14170 14180 14190 14200
DPVGPGLDIQ QLYWELSQLT HGVTQLGFYV LDRDSLFING YAPQNLSIRG
14210 14220 14230 14240 14250
EYQINFHIVN WNLSNPDPTS SEYITLLRDI QDKVTTLYKG SQLHDTFRFC
14260 14270 14280 14290 14300
LVTNLTMDSV LVTVKALFSS NLDPSLVEQV FLDKTLNASF HWLGSTYQLV
14310 14320 14330 14340 14350
DIHVTEMESS VYQPTSSSST QHFYLNFTIT NLPYSQDKAQ PGTTNYQRNK
14360 14370 14380 14390 14400
RNIEDALNQL FRNSSIKSYF SDCQVSTFRS VPNRHHTGVD SLCNFSPLAR
14410 14420 14430 14440 14450
RVDRVAIYEE FLRMTRNGTQ LQNFTLDRSS VLVDGYSPNR NEPLTGNSDL
14460 14470 14480 14490 14500
PFWAVILIGL AGLLGVITCL ICGVLVTTRR RKKEGEYNVQ QQCPGYYQSH
14507
LDLEDLQ

Data source: UniProt

Protein Map Collapse protein map

Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-2227 Collapse assay details

Data source: Panorama

Official Gene Symbol
MUC16
Peptide Modified Sequence
TSSTEGN[+1.0]FTK
Modification Type
Deamidated (N)
Protein - Site of Modification
139
Peptide - Site of Modification
7
Peptide Start
133
Peptide End
142
CPTAC ID
CPTAC-2227
Peptide Molecular Mass
1,071.4720
Species
Homo sapiens (Human)
Assay Type
Direct MRM
Matrix
Human ovarian tissue digest
Submitting Laboratory
Johns Hopkins University
Submitting Lab PI
Daniel Chan, Hui Zhang, Zhen Zhang

Assay Parameters Collapse assay parameters

Data source: Panorama

Instrument
LCMS-8040
Internal Standard
Stable isotope-labeled peptides
Peptide Standard Purity
Crude (~60%)
Peptide Standard Label Type
13C and 15N at C-terminus K
LC
Nexera X2 UHPLC
Column Packing
C18, 3 µm, 300 Å
Column Dimensions
1.0 mm I.D. x 15 cm
Flow Rate
50 µL/min

Assay Multiplexing Expand assay panel

Johns Hopkins University-G

Chromatograms

Data source: Panorama

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Response Curves

Data source: Panorama

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Retrieving Data

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Repeatability

Data source: Panorama

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  Average intra-assay CV
(within day CV)		 Average inter-assay CV
(between day CV)		 Total CV
equation		 n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y6 (1+) 30.6 14.9 18.9 20.4 17.1 18.3 36.8 22.7 26.3 15 15 15
y7 (1+) 11.7 15.2 13.6 14.8 17.8 15 18.9 23.4 20.2 15 15 15
y8 (1+) 13.5 8.1 9.7 12 6.7 10.1 18.1 10.5 14 15 15 15
sum 11.8 7.7 7.4 9.7 6 7.8 15.3 9.8 10.8 15 15 15

Additional Resources and Comments

Resources
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View Peptide in Panorama
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