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Overview Data source: UniProt

Official Gene Symbol Other Aliases
P2RX7 N/A
Sequence Length (AA) Molecular Weight (Da)
595 68585
Protein Name
P2X purinoceptor 7
Sources
UniProt
PhosphoSitePlus ®
GeneCards
Human Protein Atlas

Protein Sequence hover to view complete sequence

10 20 30 40 50
MPACCSCSDV FQYETNKVTR IQSMNYGTIK WFFHVIIFSY VCFALVSDKL
60 70 80 90 100
YQRKEPVISS VHTKVKGIAE VKEEIVENGV KKLVHSVFDT ADYTFPLQGN
110 120 130 140 150
SFFVMTNFLK TEGQEQRLCP EYPTRRTLCS SDRGCKKGWM DPQSKGIQTG
160 170 180 190 200
RCVVYEGNQK TCEVSAWCPI EAVEEAPRPA LLNSAENFTV LIKNNIDFPG
210 220 230 240 250
HNYTTRNILP GLNITCTFHK TQNPQCPIFR LGDIFRETGD NFSDVAIQGG
260 270 280 290 300
IMGIEIYWDC NLDRWFHHCR PKYSFRRLDD KTTNVSLYPG YNFRYAKYYK
310 320 330 340 350
ENNVEKRTLI KVFGIRFDIL VFGTGGKFDI IQLVVYIGST LSYFGLAAVF
360 370 380 390 400
IDFLIDTYSS NCCRSHIYPW CKCCQPCVVN EYYYRKKCES IVEPKPTLKY
410 420 430 440 450
VSFVDESHIR MVNQQLLGRS LQDVKGQEVP RPAMDFTDLS RLPLALHDTP
460 470 480 490 500
PIPGQPEEIQ LLRKEATPRS RDSPVWCQCG SCLPSQLPES HRCLEELCCR
510 520 530 540 550
KKPGACITTS ELFRKLVLSR HVLQFLLLYQ EPLLALDVDS TNSRLRHCAY
560 570 580 590 595
RCYATWRFGS QDMADFAILP SCCRWRIRKE FPKSEGQYSG FKSPY

Data source: UniProt


Position of Targeted Peptide Analytes Relative to SNPs, Isoforms, and PTMs

Uniprot Database Entry PhosphoSitePlus ®

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Phosphorylation Acetylation Ubiquitylation Other

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Assay Details for CPTAC-2229 Collapse assay details

Data source: Panorama

Official Gene Symbol
P2RX7
Peptide Modified Sequence
TTN[+1.0]VSLYPGYNFR
Modification Type
Deamidated (N)
Protein - Site of Modification
284
Peptide - Site of Modification
3
Peptide Start
282
Peptide End
294
CPTAC ID
CPTAC-2229
Peptide Molecular Mass
1,531.7307
Species
Homo sapiens (Human)
Assay Type
Direct MRM
Matrix
Human ovarian tissue digest
Submitting Laboratory
Johns Hopkins University
Submitting Lab PI
Daniel Chan, Hui Zhang, Zhen Zhang

Assay Parameters Collapse assay parameters Test button response curves

Data source: Panorama

Instrument
LCMS-8040
Internal Standard
Stable isotope-labeled peptides
Peptide Standard Purity
Crude (~60%)
Peptide Standard Label Type
13C and 15N at C-terminus R
LC
Nexera X2 UHPLC
Column Packing
C18, 3 µm, 300 Å
Column Dimensions
1.0 mm I.D. x 15 cm
Flow Rate
50 µL/min

Assay Multiplexing Expand assay panel

Johns Hopkins University-G


Chromatograms

Data source: Panorama


Response Curves

Data source: Panorama

Retrieving Data

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Repeatability

Data source: Panorama

  Average intra-assay CV
(within day CV)
Average inter-assay CV
(between day CV)
Total CV
equation
n=
Fragment ion / Transition Low Med High Low Med High Low Med High Low Med High
y7 (1+) 28.8 15.5 12.6 29.7 17.2 14 41.4 23.2 18.8 15 15 15
y6 (1+) 12.1 4.3 10 17 8.5 11.6 20.9 9.5 15.3 15 15 15
y9 (1+) 27.1 14.9 15.7 27.5 21.1 18.8 38.6 25.8 24.5 15 15 15
sum 12.2 4.5 6.4 13 8.7 6.2 17.8 9.8 8.9 15 15 15

Additional Resources and Comments